The anaphase-promoting complex or cyclosome (APC/C) is a multi-subunit ubiquitin ligase that regulates the eukaryotic cell cycle. APC/C belongs to the RING finger class of ubiquitin ligases that function by interacting with a ubiquitin-conjugating enzyme (Ubc), thus inciting the Ubc to transfer ubiquitin onto a target protein. Extensive studies with APC/C in other organisms have identified seve...

Context A recent increase in the number of publications on the high prevalence of burnout and moral distress in health professionals in general, and in critical care staff in particular, has led to a call for more research into the mechanisms by which burnout arises and into interventions to increase resilience in the workplace. In this study, the associations between exposure to pain, empathy ...

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Many aspects of plant water use -- particularly in response to soil drought -- may have as their basis the alteration of hydraulic conductance from soil to canopy. The regulation of plant water potential (Psi) by stomatal control and leaf area adjustment may be necessary to maximize water uptake on the one hand, while avoiding loss of hydraulic contact with the soil water on the other. Modellin...

This article examines the Mu‘tazilite Qādī ‘Abd al-Jabbār’s views on the denotation of miracles according to his own particular methodology. Despite his acceptance of the celebrated method of the theologians in the denotation of miracles with respect to the authenticity of prophets, i.e., resorting to divine wisdom, Qādī ‘Abd al-Jabbār instead proposed the issue within the structure of conven...

Previous research strongly suggests that morphologically complex words are recognized in terms of their constituent morphemes. A question thus arises as to how the recognition system codes for morpheme position within words, given that it needs to distinguish morphological anagrams like overhang and hangover. The present study focused specifically on whether the recognition of suffixes occurs i...