Paranasal sinus osteomas are benign osteogenic lesions, often diagnosed incidentally on computed tomography (CT). Their etiology is unknown, and they most commonly involve the frontal and ethmoid sinus. We present an exceedingly rare localization of osteoma within the cavity of a concha bullosa of the middle turbinate in a 38-year-old woman with frontal headaches and right-sided facial pain. Th...

Julia Spoendlin, Johannes J. Voegel, Susan S. Jick and Christoph R. Meier Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacy and Epidemiology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland; Hospital Pharmacy, University Hospital Basel, Basel, Switzerland; Galderma Research & Development, Sophia Antipolis, France and Boston Collaborative Drug Surveill...

Patients with epidermolysis bullosa (EB) provide a unique and complex challenge for the anaesthesiologist. This is rare inherited group of diseases characterized by excessive fragility skin mucous membranes. These patients tolerate compressive forces to but barely friction shearing forces. Major challenges anaesthetist include establishing adequate monitoring without damaging skin, issues posit...

Dystrophic epidermolysis bullosa pruriginosa (DEB-Pr) is a rare subtype of dystrophic epidermolysis bullosa (DEB). This disease is characterized by severe itching, lichenoid nodules or prurigo-like lesions, and linear scarring with a predilection for the extensor limbs. Pathogenic mutations in the type VII collagen alpha 1 (COL7A1) gene have been identified. We analyzed mutations in the COL7A1 ...

INTRODUCTION Mycosis fungoides, the most common type of cutaneous T-cell lymphoma, can manifest in a variety of clinical and histological forms. Bulla formation is an uncommon finding in mycosis fungoides and only approximately 20 cases have been reported in the literature. CASE PRESENTATION We present a case of rapidly progressive mycosis fungoides in a 68-year-old Caucasian man who initiall...