نتایج جستجو برای: bulinus truncates

تعداد نتایج: 486  

Journal: :Frontiers in Environmental Science 2022

Mountains are considered island-like systems often characterized by exceptional biodiversity and endemism. There many highly isolated mountain ranges in Africa that collectively have been called the Afromontane archipelago. Freshwater snails of genus Bulinus composed veterinary biomedical important species. These intermediate hosts for schistosomiasis parasites wide spread some species to be ad...

2017
Suzy J. Campbell J. Russell Stothard Faye O’Halloran Deborah Sankey Timothy Durant Dieudonné Eloundou Ombede Gwladys Djomkam Chuinteu Bonnie L. Webster Lucas Cunningham E. James LaCourse Louis-Albert Tchuem-Tchuenté

BACKGROUND The crater lakes of Barombi Mbo and Barombi Kotto are well-known transmission foci of schistosomiasis and soil-transmitted helminthiasis having had several important control initiatives previously. To collect contemporary epidemiological information, a cross-sectional survey was undertaken inclusive of: signs and symptoms of disease, individual treatment histories, local water, sanit...

2012
Emma Jane Smith Rebecca M Corrigan Tetje van der Sluis Angelika Gründling Pietro Speziale Joan A Geoghegan Timothy J Foster

The Sbi protein of Staphylococcus aureus comprises two IgG-binding domains similar to those of protein A and a region that triggers the activation of complement C3. Sbi is expressed on the cell surface but its C-terminal domain lacks motifs associated with wall or membrane anchoring of proteins in Gram-positive bacteria. Cell-associated Sbi fractionates with the cytoplasmic membrane and is not ...

Journal: :Science 2014
Nikolai A Naryshkin Marla Weetall Amal Dakka Jana Narasimhan Xin Zhao Zhihua Feng Karen K Y Ling Gary M Karp Hongyan Qi Matthew G Woll Guangming Chen Nanjing Zhang Vijayalakshmi Gabbeta Priya Vazirani Anuradha Bhattacharyya Bansri Furia Nicole Risher Josephine Sheedy Ronald Kong Jiyuan Ma Anthony Turpoff Chang-Sun Lee Xiaoyan Zhang Young-Choon Moon Panayiota Trifillis Ellen M Welch Joseph M Colacino John Babiak Neil G Almstead Stuart W Peltz Loren A Eng Karen S Chen Jesse L Mull Maureen S Lynes Lee L Rubin Paulo Fontoura Luca Santarelli Daniel Haehnke Kathleen D McCarthy Roland Schmucki Martin Ebeling Manaswini Sivaramakrishnan Chien-Ping Ko Sergey V Paushkin Hasane Ratni Irene Gerlach Anirvan Ghosh Friedrich Metzger

Spinal muscular atrophy (SMA) is a genetic disease caused by mutation or deletion of the survival of motor neuron 1 (SMN1) gene. A paralogous gene in humans, SMN2, produces low, insufficient levels of functional SMN protein due to alternative splicing that truncates the transcript. The decreased levels of SMN protein lead to progressive neuromuscular degeneration and high rates of mortality. Th...

Journal: :Genetics 1998
D F Eberl D Ren G Feng L J Lorenz D Van Vactor L M Hall

To begin unraveling the functional significance of calcium channel diversity, we identified mutations in Dmca1D, a Drosophila calcium channel alpha1 subunit cDNA that we recently cloned. These mutations constitute the l(2)35Fa lethal locus, which we rename Dmca1D. A severe allele, Dmca1D(X10), truncates the channel after the IV-S4 transmembrane domain. These mutants die as late embryos because ...

2000
Raphael Bousso

We argue that the total observable entropy is bounded by the inverse of the cosmological constant. This holds for all space-times with a positive cosmological constant, including cosmologies dominated by ordinary matter, and recollapsing universes. The argument involves intermediate steps which may be of interest in their own right. We note that entropy cannot be observed unless it lies both in...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2001
F Van Goor Y X Li S S Stojilkovic

Activation of high-conductance Ca(2+)-activated K(+) (BK) channels normally limits action potential duration and the associated voltage-gated Ca(2+) entry by facilitating membrane repolarization. Here we report that BK channel activation in rat pituitary somatotrophs prolongs membrane depolarization, leading to the generation of plateau-bursting activity and facilitated Ca(2+) entry. Such a par...

2004
Limin Peng Jason P. Fine

SUMMARY Cause-specific hazard and cumulative incidence function are of practical importance in competing risks studies. Inferential procedures for these quantities are well developed and can be applied to semi-competing risks data, where a terminating event censors a non-terminating event, after coercing the data into the competing risks format. Complications arise when there is left truncation...

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