We studied the levels of twenty two free amino acids in the striatum and olfactory bulb of mice treated during nine weeks with daily intraperitoneal injections of manganese chloride at a concentration of 5.0 mg Mn+2/kg body weight. In the olfactory bulb the contents of alanine, alpha-amino-n-butyrate, arginine, asparagine, aspartate, citrulline, GABA, glutamate, glycine, isoleucine, leucine, me...

The vomeronasal system, including the vomeronasal organ, the accessory olfactory bulb and higher centers, functions to detect substances associated with social and reproductive behavior (Wysocki, 1979; Halpern, 1987). The vomeronasal epithelium has a structure similar to that of the olfactory epithelium, consisting of receptor neurons, supporting cells and precursor cells (Matsuoka et al., 2000...

Fez is a zinc-finger gene encoding a transcriptional repressor that is expressed in the olfactory epithelium, hypothalamus, ventrolateral pallium and prethalamus at mid-gestation. To reveal its function, we generated Fez-deficient mice. The Fez-deficient mice showed several abnormalities in the olfactory system: (1) impaired axonal projection of the olfactory sensory neurons; (2) reduced size o...

The hair follicle consists of several distinctive epidermal cell layers. The hair root, which undergoes keratinization, is surrounded by two sheaths: the inner root sheath (IRS) and the outer root sheath (ORS). The ORS is continuous with the basal layer of the epidermis. Its cells do not keratinize in situ, unlike IRS. We have previously demonstrated that keratinization of the ORS was prevented...

The comparative performance of shaded and unshaded Zebu cross steers was studied in a Queensland feedlot from January to May 1992. The provision of shade gave no significant (P > 0.05) advantage in liveweight gain (182 V. 177 kg), feed conversion ratio (9.4 v. 9.8 kg of fresh feed/kg liveweight gain), carcase weight, dressing percentage, P8 rump fat, eye muscle area, saleable meat yield, meat c...

Imprinting ensures that the infant forms the caregiver attachment necessary for altricial species survival. In our mammalian model of imprinting, neonatal rats rapidly learn the odor-based maternal attachment. This rapid learning requires reward-evoked locus ceruleus (LC) release of copious amounts of norepinephrine (NE) into the olfactory bulb. This imprinting ends at postnatal day 10 (P10) an...