Tuberculosis of the oral cavity is a very rare disease and accounts for less than one percent of all cases of tuberculosis. Primary lesions are extremely rare. Presentation is as a single ulcer, may be painful, however multiple painless ulcers have been described. Tongue is the most common oral site involved. The palate, buccal mucosa, floor of the mouth, gingiva, and lips are other possible si...

BACKGROUND Exogenous or endogenous hydrogen peroxide (H2O2) is a reactive oxygen species (ROS) that can lead to oxidation of cellular nucleophiles, particularly cysteines in proteins. Commercial mouthwashes containing H2O2 provide the opportunity to determine clinically whether changes in S-glutathionylation of susceptible proteins in buccal mucosa cells can be used as biomarkers of ROS exposur...

Solitary fibrous tumors are rare spindle cell neoplasms that typically occur in the thorax but have been described in various locations within the abdomen and head and neck region. The most common extrapleural site is the oral cavity, but these tumors have been also described in the orbit, nasopharynx, paranasal sinuses, salivary glands, and larynx. We describe a case of a solitary fibrous tumo...

Rhabdomyosarcoma is the malignant neoplasm of striated muscle and a relatively uncommon tumor of the oral cavity. Embryonal variety is the most common subtype, observed in children below 10 years of age but occasionally seen in adolescents and young adults. The present report describes a case of embryonal rhabdomyosarcoma in the left posterior buccal mucosa, with extension in the adjacent alveo...

Mucoadhesive buccal patches containing propranolol hydrochloride were prepared using the solvent casting method. Chitosan was used as bioadhesive polymer and different ratios of chitosan to PVP K-30 were used. The patches were evaluated for their physical characteristics like mass variation, drug content uniformity, folding endurance, ex vivo mucoadhesion strength, ex vivo mucoadhesion time, su...

Diagnosis of the disease by dentists and other clinicians through the evaluation of oral clinical findings is a rare incident. Mucocutaneous and granulomatous lesions of the oral cavity alert the clinician to investigate the gastrointestinal tract. This review highlights oral manifestations of gastrointestinal disorders, how various diseases and their presentations are integrated and intertwine...

Hemangiomas of the head and neck are benign tumours that have their origin from blood vessels. classified as capillary, cavernous , sclerosing central type. The nature this tumour is progressively slow growing, including involvement greater portions superficial deep vessels, functions maybe affected, depending on location. common in rare occurrence oral cavity. Lips, buccal mucosa tongue sites,...

Granisetron hydrochloride is most commonly used as an antiemetic agent in treatment associated with cancer chemotherapy induced nausea and vomiting. If the dosage form is designed in sustain release it provide more advantage for the antiemetic therapy. The purpose of this research was to study mucoadhesive buccal patches of Granisetron hydrochloride using the bioadhesive polymers chitosan and s...

Present study investigated the protective effect of apigenin on cell surface glycoconjugates abnormalities in 7, 12-dimethyldenz(a)anthracene(DMBA) induced hamster buccal pouch carcinogenesis. DMBA painting in the hamster buccal pouch three times per week for 14 weeks developed oral squamous cell carcinoma. The levels of glycoconjugates (Protein bound hexose, Hexosamine, Lipid bound sialic acid...

background the dilution and rapid elimination of topically applied drugs due to the flushing action of saliva is a major difficulty in the effort to eradicate infections of oral cavity. utilization a proper delivery system for incorporation of drugs has a major impact on drug delivery and such a system should be formulated for prolonged drug retention in oral cavity. objectives the aim of the p...