TO THE EDITOR—We thank Cunnington et al [1] for their constructive criticism. They acknowledge that " [n]umerous studies have confirmed the association of parasite sequestration with fatal malaria " but offer an alternate hypothesis, " that extensive sequestration is simply a consequence of endothelial activation and microvascular dysfunction " [1]. However, if sequestration is simply an epiphe...

administration revealed significantly lower test values in the group of patients exposed to RBC (P = 0.002) [2]. The role of ASA and CLO administration management should be separately assessed by drug-specific platelet function tests, thus facilitating an individual therapeutic approach for each antiplatelet agent preoperatively. In addition, intraoperative assessment of platelet function and v...

same RHAMM1v4 isoform expressed in the same cells RHAMM belongs to a group of hyaladherins that reguwas later reported to be located exclusively in the cytolate cell motility and cell cycle and that are expressed plasm (Zhang et al., 1998). in the cytoplasm, nucleus, and cell surface, in spite of Questions about the physiological significance of the a lack of signal peptide or transmembrane dom...

Cleidocranial dysplasia is a autosomal dominant inherited disorder, and it is the primary disorder of the bone. When the clinicians’ suspect this syndrome, they check for the presence of clavicles. In the literature, yet several other features are reported. Several researches including Chromosomal studies and dermatoglyphics are carried out, for the prevention and management strategies’. This r...

care use and serious infection prevalence associated with penicillin " allergy " in hospitalized patients: a cohort study.ation of the impact of antibiotic stewardship on reducing the use of high-risk antibiotics and its effect on the incidence of Clostridium difficile infection in hospital settings. The impact of penicillin skin testing on clinical practice and anti-microbial stewardship. Shen...

TO THE EDITOR—In a recent letter, Zhang et al expressed concerns on our recent report on hypervirulent Klebsiella pneumoniae (hvKP) in China [1, 2]. We would like to address their points of concerns. First, Zhang et al stated that “the genetic relatedness of clinical isolates should be further identified by molecular analysis” [2]. It is generally agreed in publications and clinical practice th...

The Journal of Infectious Diseases® 2017;215:486–7 Nitazoxanide was commenced at a dose of 500 mg twice daily. It was well tolerated with no adverse effects. Initially, an improvement in frequency and severity of diarrhea was noted. Results of PCR analysis of stool specimens became negative for norovirus; however, the MS2 bacteriophage used as an internal control added to the patient sample was...

e120–5. [2] Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma. J Thorac Oncol 2011;6:244–85. [3] Van Schil PE, Asamura H, Rusch VW, Mitsudomi T, Tsuboi M, Brambilla E et al. Surgical impli...

We thank Hickey et al. [1] for their insightful comments with regard to our validation study on EuroSCORE II [2]. With regard to the era of patients, a time bias almost certainly does exist. This is a limitation of many retrospective singleinstitution validation studies, as most units do not have the number, and thus the statistical power, to use a small reference time period. It has already be...