The number of clinical studies on gamma interferon (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha) and interleukin-4 (IL-4) in human brucellosis is limited. The present study was focused on IFN-gamma, TNF-alpha and IL-4 levels in acute brucellosis cases, in the acute phase and at the end of the treatment. The relation of these cytokines to traditional inflammation markers was also investig...

BACKGROUND Brucellosis is a major public health problem in developing countries and has remained endemic in Iran. The aim of this study was to investigate the Seroprevalence of Brucellosis among high risk individuals in Guilan, Iran. METHODS In a cross-sectional study, 478 blood samples from people living in rural areas (n = 292) and 186 slaughterhouse workers were screened by slide agglutina...

AIM To analyse clinical, laboratory and epidemiological characteristics of brucellosis in children in Bosnia and Herzegovina. METHODS The study included 246 children aged 0-18 years, who were hospitalized in Clinics and Departments for Infectious Diseases in Tuzla, Sarajevo, Banja Luka, Zenica and Bihać in the period 2000-2013, in whom the diagnosis of brucellosis was established based on ana...

BACKGROUND Human brucellosis is common in southern Israel among the semi-nomadic Bedouin, a population that consumes unpasteurized dairy products. Though camel milk ingestion is a known mechanism for brucellosis acquisition, only a few reports of sporadic cases have been published in the medical literature. OBJECTIVES To describe a local brucellosis outbreak in 15 extended Bedouin family memb...

BACKGROUND Brucellosis is one of the important multi-organ zoonotic infectious diseases. The forms of the clinical course of brucellosis in humans are acute, sub-acute and chronic. OBJECTIVES The present study aimed to retrospectively analyze the clinical characteristics and complications in the clinical forms of human brucellosis in Iran. PATIENTS AND METHODS The population included 957 pa...

BACKGROUND Human brucellosis has a serious medical impact worldwide, and its eradication poses major difficulties. Although human brucellosis is relatively rare in the United States (approximately 100 cases per year), there is concern that this disease is largely underdiagnosed and underreported. Additionally, immigrants from endemic areas are arriving to this country, and Brucella species are ...

Brucellosis in goats is mainly caused by B. melitensis, although this pathogen may also infect cattle and other ruminants [1]. This pathogen has three different biovars [2]. B. melitensis was the first species in the genus Brucella described and was first isolated by Bruce in 1887 [3] from the spleens of soldiers dying of Mediterranean fever on the island of Malta. The origin of the disease rem...

Brucellosis is an occupational hazard in animal handlers and medical practitioners. This study was aimed to estimate the sero-prevalence of brucellosis in goats, sheep and butchers (slaughterhouse worker) in Quetta and its suburb. A total of 530 peripheral blood samples were collected randomly from goats (n=250), sheep (n=250) and butchers (n=30). The serum samples were subjected for Rose Benga...

Brucellosis is a highly contagious bacterial disease of both animals and humans. Infection of the female reproductive tract may result in abortion. The most common route of transmission is thought to be oral as a result of licking or ingestion of infected fetuses, placentas, fetal fluids, or vaginal exudates. Such transmission can be exacerbated under conditions that artificially congregate inf...

BACKGROUND/AIM In Serbia brucellosis is a primary disease of the animals in the southern parts of the country. The aim of this study was to describe the first outbreak of human and animal brucellosis in the region of Sabac, Serbia. METHODS An epidemiological investigation was conducted to identify a source of outbreak and the ways of transmission of brucellosis infection in human population. ...