Fibrinogen Dusart is a congenital dysfibrinogenemia (A-alpha 554 Arginine-->Cysteine) associated with severe thrombotic disorder, high incidence of thrombotic embolism, and abnormal fibrin polymerization. This thrombotic disorder was attributed to an abnormal clot thrombolysis with reduced plasminogen binding to fibrin and defective plasminogen activation by tissue plasminogen activator. The pu...

Brillouin scattering-based distributed optical fiber (OF) sensing technique presents advantages for concrete structure monitoring. However, the existence of spatial resolution greatly decreases strain measurement accuracy especially around cracks. Meanwhile, the brittle feature of OF also hinders its further application. In this paper, the distributed OF sensor was firstly proposed as long-gaug...

A doped poly(methyl methacrylate) (PMMA)– based graded-index plastic optical fiber (GI POF) with high mechanical strength is reported for the first time. Although the POF is generally believed to have a good mechanical flexibility even if it has a large-core diameter, such a high mechanical strength has been provided by making the polymer chains in the POF highly oriented in its axial direction...

AIMS To determine the long-term (20 years from presentation) outcome of brittle type 1 diabetes characterized by recurrent episodes of ketoacidosis (DKA). METHODS The cohort studied was a group of brittle diabetic patients from various parts of UK originally identified between 1979 and 1985. Patients were traced, where possible, via their diabetic clinics and/or general practitioners. Data on...

the new non-conventional cutting process by the use of thermal shock is a convenient procedure for cutting the brittle materials such as glasses and ceramics. this method is based on the application of localized thermal shock to brittle materials by the use of hot air jet, which induces thermal stresses at the tip of an existed pre-crack. due to the thermo-elastic behavior of materials, the pre...

Owing to a lack of microstructure, glassy materials are inherently strong but brittle, and often demonstrate extreme sensitivity to flaws. Accordingly, their macroscopic failure is often not initiated by plastic yielding, and almost always terminated by brittle fracture. Unlike conventional brittle glasses, metallic glasses are generally capable of limited plastic yielding by shear-band sliding...

Based on the experiment of damaged RC columns strengthened with GFRP strips and steel fiber mortar, this paper established a model using ABAQUS to perform finite element simulation analysis extended factors such as spacing strips, number layers strength mortar. The results indicate that: smaller more bring stronger constraint core part, larger peak load composite structure better ductility; mor...