1. An accurate quantitative method of measuring the penetration of dye into the living cell is described. 2. Cresyl blue is unable to penetrate rapidly unless the pH outside the cell is decidedly greater than that inside. The rate of penetration increases with increasing pH. 3. Around pH 9 penetration of the dye is rapid while the reverse is true of exosmosis. At low pH values (5.9) exosmosis i...

Title of thesis: INTEGRATION OF BENZOCYCLOBUTENE POYMERS AND SILICON MICROMACHNED STRUCTURES FABRICATED WITH ANISOTROPIC WET ETCHING Nima Ghalichechian, Master of Science, 2005 Thesis directed by: Professor Reza Ghodssi Department of Electrical and Computer Engineering Integration of low dielectric constant Benzocyclobutene (BCB) film with deep etched structures in silicon allows the fabricatio...

Brilliant blue G (BBG), best known as an antagonist of P2X7 receptors, was found to inhibit voltage-gated sodium currents in N1E-115 neuroblastoma cells. Sodium currents elicited from a holding potential of -60 mV were blocked with an IC(50) of 2 μM. Block was enhanced in a use-dependent manner at higher stimulation rates. The voltage-dependence of inactivation was shifted in the hyperpolarizin...