نتایج جستجو برای: breast cancer risk
تعداد نتایج: 1808040 فیلتر نتایج به سال:
the increasing prevalence rate of breast cancer among asian-american women shows the more significant role of lifestyle factors in etiology than genetic factors. the search engine pubmed was used for searching related paper by “breast cancer”, “soy”, “isoflavones”, “phytoestrogen” as the key words. we selected papers which published during 1990 to 2012. various experimental studies reported the...
Background:Dysregulation of HOX Transcript Antisense Intergenic RNA (HOTAIR) has been linked to the etiopathogenesis of several human cancers. According to epidemiological evidences, the risk of susceptibility to breast cancer varies among different populations. This study was designed to determine the transcriptional level of HOTAIR in tumor cells of breast cancer pat...
patients and methods in this cross-sectional study, data of 584 female patients (mean age of 45.9 years) referred to breast cancer research center (tehran, iran) were analyzed anonymously. spss and norm softwares (2.03) were used for data transformation, running and interpretation of cca and replacing missing values, respectively. data were obtained from breast cancer research center, tehran, i...
Introduction: There is a close relationship between the incidence of breast cancer and fat intake in different populations. Overweight and obesity during menopause can increase the risk of breast cancer in women. Hormones like estrogen and leptin are factors that affect the growth and proliferation of breast cells. The main purpose of this study was to evaluate the relationships between body ma...
the ataxia telangiectasia mutated gene (atm), candidate for breast cancer susceptibility gene, encode a 350-kda protein belongs to the core components of dna-damage response machinery. female at carriers have at least 5-fold increase risk for breast cancer. reduction in atm expression is shown in multiple studies in breast tissues. we aimed to perform a research to measure the atm mrna expressi...
Introduction: Breast cancer is the most common cancer among women and the risk is higher among women who have close relatives with breast cancer. So the aim of this study was to investigate the prevalence and barriers to mammography in close relatives of breast cancer patients in sirjan. Methods: The study population consisted of 65 women, all close relatives (First-degree relatives including ...
Background & Objective: Sex Hormone-Binding Globulin (SHBG) is a plasma glycoprotein that regulates the action of steroid hormones on several levels. Since SHBG is one of the growth regulators of breast cancer cells, the aim of this study was to evaluate the association between polymorphisms E326K and the risk of breast cancer. Materials & Methods: This study was done as a case-control study on...
Background and Aim: ESR1 gene polymorphism has been found to be associated with breast cancer and clinical features of the disease in Caucasians. Genomic data for ESR1 in either population is therefore of value in the clinical setting for that ethnic group. In this study association of polymorphism in ESR1 gene with breast cancer risk was investigated. Materials and Methods: A case-control stud...
Breast cancer is the most common cancer in women. Several risk factors such as age, family history of breast cancer, marital status, early menarche and late menopause are related to breast cancer. Obesity is also a main health problem associated with breast cancer incidence and subsequent mortality. Association between obesity and expansion of breast cancer may be due to excessive sex steroid h...
Introduction: Breast cancer is the most common malignancy worldwide, which affects women. Also, this disease is one of the most frequent malignancies among women in Iran. Apoptosis is a known mechanism against cancer, which has intrinsic and extrinsic pathways. One of these extrinsic pathways, is Fas receptor-ligand system, which plays a key role in apoptotic signaling in many cell types, parti...
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