Abstract This review aimed to assess the antioxidant properties of safrole, myristicin, and terpineol from Myristica fragrans Houtt. Safrole exhibited high cytotoxic activities against numerous cancer cell lines also shown able suppress tumor angiogenesis. Myristicin is increase activity glutathione peroxidase (GPX), reductase (GR) or glutathione-disulfide-reductase (GSR), superoxide dismutase ...

The long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been recently shown to be dysregulated in several cancers. However, the mechanisms underlying the role of MALAT1 in breast cancer remain unclear. Herein, we showed that MALAT1 was aberrantly increased in breast cancer tissues and cells. MALAT1-siRNA inhibited breast cancer cell proliferation and...

BACKGROUND Breast cancer is the most common type of malignancy in the female population, rarely is reported by thromboembolic events during the course of the disease. In this case, we present a rare case of breast cancer presenting as deep vein thrombosis of the axillary vein. CASE PRESENTATION A 40-year- old female was admitted due to pain and swelling of her right arm and forearm of two mon...

In this report, we describe a novel cDNA isolated from a primary human breast adenocarcinoma and differentially expressed in several breast carcinoma cell lines. The protein encoded by this cDNA, which we have named mammaglobin, is homologous to a family of secreted proteins that includes rat prostatic steroid-binding protein subunit C3, human Clara cell 10-kilodalton protein, and rabbit uterog...

Metastasis to the breast represents 0.4-1.3% of all breast malignancies. In those rare instances, the primary site is usually leukemia, lymphoma, or melanoma. Lung cancer, mostly adenocarcinoma, has been reported to be associated with metastasis to the breast. We report a rare case of a female patient with a rapidly growing breast metastasis from a small cell lung cancer, as a first site of rec...

1 Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, United States, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, United States, Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, United States, Department of Biochemistry and Molecular Biolog...

Metastasis of breast cancer to lung, bone and liver is common, but metastasis to ovaries is rare in Korea. A 31-year-old woman diagnosed with breast cancer was referred to our department due to a newly detected adnexal mass via abdomen sonography during regular check-up. Imaging studies revealed solid mass on left ovary and enlarged lymph nodes. She underwent a laparotomy including hysterectomy...