نتایج جستجو برای: brain volumes

تعداد نتایج: 519830  

2017
Eva L. Dyer William Gray Roncal Hugo L. Fernandes Doga Gürsoy Xianghui Xiao Joshua T. Vogelstein Chris Jacobsen Konrad P. Körding Narayanan Kasthuri

Methods for resolving the three-dimensional (3D) microstructure of the brain typically start by thinly slicing and staining the brain, followed by imaging numerous individual sections with visible light photons or electrons. In contrast, X-rays can be used to image thick samples, providing a rapid approach for producing large 3D brain maps without sectioning. Here we demonstrate the use of sync...

Journal: :Biological psychology 2002
Dorit Carmelli Gary E Swan Charles DeCarli Terry Reed

As part of an ongoing longitudinal twin study, data from both MRI brain scanning and from neuropsychological testing were obtained from 139 male-male twin pairs (72 monozygotic [MZ] and 67 dizygotic [DZ]), 69-80 years old at the time of examination. For descriptive purposes, we examined the MZ and DZ intraclass correlations (ICC) of four lobar brain volumes (frontal, temporal, parietal, and occ...

2016
Antonios Makropoulos Paul Aljabar Robert Wright Britta Hüning Nazakat Merchant Tomoki Arichi Nora Tusor Joseph V. Hajnal A. David Edwards Serena J. Counsell Daniel Rueckert

Detailed morphometric analysis of the neonatal brain is required to characterise brain development and define neuroimaging biomarkers related to impaired brain growth. Accurate automatic segmentation of neonatal brain MRI is a prerequisite to analyse large datasets. We have previously presented an accurate and robust automatic segmentation technique for parcellating the neonatal brain into mult...

Journal: :Human brain mapping 2014
Florence F Roussotte Neda Jahanshad Derrek P Hibar Elizabeth R Sowell Omid Kohannim Marina Barysheva Narelle K Hansell Katie L McMahon Greig I de Zubicaray Grant W Montgomery Nicholas G Martin Margaret J Wright Arthur W Toga Clifford R Jack Michael W Weiner Paul M Thompson

Delta opioid receptors are implicated in a variety of psychiatric and neurological disorders. These receptors play a key role in the reinforcing properties of drugs of abuse, and polymorphisms in OPRD1 (the gene encoding delta opioid receptors) are associated with drug addiction. Delta opioid receptors are also involved in protecting neurons against hypoxic and ischemic stress. Here, we first e...

Journal: :Journal of magnetic resonance imaging : JMRI 2008
William R Riddle Susan C DonLevy Curtis A Wushensky Benoit M Dawant J Michael Fitzpatrick Ronald R Price

PURPOSE To identify and quantify structural changes in the maturing brain between childhood and adolescence. MATERIALS AND METHODS Two three-dimensional T1-weighted MR volumes of the brain were acquired from eight subjects, 6 to 7 years apart. The subjects were 9 to 12 years old on the first scan and 15 to 19 years old on the second scan. The MR scans were converted to one millimeter isotropi...

2016
Camille Garcia-Ramos Jack J Lin Leonardo Bonilha Jana E Jones Daren C Jackson Vivek Prabhakaran Bruce P Hermann

Anxiety disorders represent a prevalent psychiatric comorbidity in both adults and children with epilepsy for which the etiology remains controversial. Neurobiological contributions have been suggested, but only limited evidence suggests abnormal brain volumes particularly in children with epilepsy and anxiety. Since the brain develops in an organized fashion, covariance analyses between differ...

Journal: :Journal of child psychology and psychiatry, and allied disciplines 2006
Gregory L Wallace J Eric Schmitt Rhoshel Lenroot Essi Viding Sarah Ordaz Michael A Rosenthal Elizabeth A Molloy Liv S Clasen Kenneth S Kendler Michael C Neale Jay N Giedd

BACKGROUND Longitudinal pediatric neuroimaging studies have demonstrated increasing volumes of white matter and regionally-specific inverted U shaped developmental trajectories of gray matter volumes during childhood and adolescence. Studies of monozygotic and dyzygotic twins during this developmental period allow exploration of genetic and non-genetic influences on these developmental trajecto...

Journal: :Journal of occupational and environmental medicine 2010
Brian S Schwartz Brian Caffo Walter F Stewart Haley Hedlin Bryan D James David Yousem Christos Davatzikos

OBJECTIVE : We evaluated whether tibia lead was associated with longitudinal change in brain volumes and white matter lesions in male former lead workers and population-based controls in whom we have previously reported on the cognitive and structural consequences of cumulative lead dose. METHODS : We used linear regression to identify predictors of change in brain volumes and white matter le...

Journal: :Pediatrics 2005
Catherine Limperopoulos Janet S Soul Kimberlee Gauvreau Petra S Huppi Simon K Warfield Haim Bassan Richard L Robertson Joseph J Volpe Adré J du Plessis

OBJECTIVE Cognitive impairments and academic failure are commonly reported in survivors of preterm birth. Recent studies suggest an important role for the cerebellum in the development of cognitive and social functions. The objective of this study was to examine the impact of prematurity itself, as well as prematurity-related brain injuries, on early postnatal cerebellar growth with quantitativ...

Journal: :Human brain mapping 2012
Florence F Roussotte Kathleen K Sulik Sarah N Mattson Edward P Riley Kenneth L Jones Colleen M Adnams Philip A May Mary J O'Connor Katherine L Narr Elizabeth R Sowell

Individuals with heavy prenatal alcohol exposure can experience significant deficits in cognitive and psychosocial functioning and alterations in brain structure that persist into adulthood. In this report, data from 99 participants collected across three sites (Los Angeles and San Diego, California, and Cape Town, South Africa) were analyzed to examine relationships between brain structure, ne...

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