Conjunctival malignant melanoma is a rare tumor with a high risk of local recurrence, lymph node and systemic metastases. The aim of this study was to correlate tumor thickness, tumor ulceration, high mitotic rate, epithelioid cells with the presence of metastases and death from conjunctival malignant melanoma. We report the case of a 33-year-old patient who presented with a left eyelid ptosis ...

Abstract Background Patients who have been treated with reirradiation for recurrent glioma reported survival benefits. This study aims to investigate whether re-irradiation of 45Gy dose can increase the overall patients. Material and Methods A retrospective analysis 35 patients re-irradiated high-grade recurrence between 2012 2020 was performed. All included met following criteria: a) histopath...

Glomus tympanicum is a rare tumor. It classified as tumor of auricular system but there high rate recurrence. In this article, the authors present case female patient with glomus tympanicum. The has experiences 4 times recurrence within 5 years after first diagnosis. Full text available online at https://drive.google.com/open?id=1Q_2IJ_rIGv5vRsi4acRAdgIAZlx4Uvmb

Brain glioma is the most common primary intracranial tumor characterized by dismal prognosis and frequent recurrence, yet a real-time and reliable biological approach to monitor tumor response and progression is still lacking. Recently, few studies have reported that circulating tumor cells (CTCs) could be detected in glioblastoma multiform (GBM), providing the possibility of its application in...

Malignant glioma is one of the most challenging central nervous system (CNS) diseases, which is typically associated with high rates of recurrence and mortality. Current surgical debulking combined with radiation or chemotherapy has failed to control tumor progression or improve glioma patient survival. Microbubbles (MBs) originally serve as contrast agents in diagnostic ultrasound but have rec...

Glioblastoma multiforme is the most common and fatal primary brain tumor in adults. Aggressive invasion of glioblastoma cells into brain tissue often limits complete surgical resection and contributes to therapeutic resistance. The cell surface marker, CD133, has been identified as a putative stem cell marker in normal and malignant brain tissues; CD133-/A2B5+ cells exhibit neural stem-like cel...

Abstract Background Sinonasal inverted papilloma or Schneiderian is a rare benign tumor of paranasal sinuses and nasal cavities. It can cause bone remodeling has significant malignant potential. Hence, it very important to diagnose treat the at earliest. Recurrence occur even after surgical extensive resection. Case presentation This case report highlights 36-year-old male patient who presented...

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is used to track the first pass of an exogenous, paramagnetic, nondiffusible contrast agent through brain tissue, and has emerged as a powerful tool in the characterization of brain tumor hemodynamics. DSC-MRI parameters can be helpful in many aspects, including tumor grading, prediction of treatment response, likelihood of ma...

Abstract BACKGROUND With improved systemic therapy that has limited impact on the intracranial compartment, incidence of brain metastasis (BM) from solid cancers is rising. Treatment varies based presentation, however, for patients with < 4 symptomatic BMs current clinical practice involves surgical resection followed by stereotactic radiosurgery (SRS) to cavity. Post-operative SRS assoc...

BACKGROUND Glioblastoma is an aggressive and highly infiltrative brain cancer. Standard surgical resection is guided by enhancement on postcontrast T1-weighted (T1) magnetic resonance imaging, which is insufficient for delineating surrounding infiltrating tumor. OBJECTIVE To develop imaging biomarkers that delineate areas of tumor infiltration and predict early recurrence in peritumoral tissu...