A 33-year-old woman presented with rare brain metastases from undifferentiated high-grade sarcoma manifesting as headache and vomiting. Magnetic resonance (MR) imaging demonstrated multiple tumors in the brain, subcutaneous soft tissue, and mediastinum. The patient underwent surgery, followed by chemotherapy and radiotherapy. The histological diagnosis was undifferentiated high-grade sarcoma. R...

Glioblastoma Multiforme is a grade IV detrimental tumor occurring in nearly 13,000 Americans annually, presenting serious and often fatal toll on the individual suffering from tumor. However, resistant properties of cells which together form pose variety issues terms treatment, including violently spreading throughout central nervous system, disrupting blood-brain barrier, as well having surviv...

Human cytomegalovirus (HCMV) causes persistent infection in humans and severe diseases in fetus andimmunocompromised individuals. Although HCMV is not currently implicated in human cancer, emerging evidence suggests that HCMV infection might be specifically associated with some human malignancies including glioma. Glioma is one of the most common brain tumors affecting children and adults. In t...

BACKGROUND The functional diffusion map (fDM) has been suggested as a tool for early detection of tumor treatment efficacy. We aim to study 3 factors that could act as potential confounders in the fDM: areas of necrosis, tumor grade, and change in tumor size. METHODS Thirty-four pediatric patients with brain tumors were enrolled in a retrospective study, approved by the local ethics committee...

UNLABELLED The aim of the present study was to determine the clinical feasibility of integration of stereotactic SPECT (sSPECT) with 201Tl in the stereotactic MRI (sMRI)-based planning of brain tumor biopsy. Furthermore, the predictive value of the integrated techniques was analyzed by comparison with the corresponding histologically determined metabolic activity. METHODS Ten patients underwe...

BACKGROUND: Glioma is the most common primary malignant brain tumor. Nuclear factor κB (NF-κB) has emerged as a regulator of phenotype in glioma, and particular glioblastoma multiforme, with clear relation to tumor size, recurrence, invasiveness. AIM: The aim study was analysis NF-κB expression gliomas different histologic types grades its correlation various clinicopathologic indicators. METHO...

purpose: this study was conducted to assess cognitive impairments, depression, anxiety and quality of life among patients with brain tumor and healthy adults, comparatively. methods: a cross-sectional study was administrated on 84 brain tumor patients and 84 healthy adults measured by the mini mental state examination, beck, hamilton and sf36 questionnaires before and after 10 days of surgery. ...

INTRODUCTION The most common primary tumors of brain are gliomas and tumor grading is essential for designing proper treatment strategies. The gold standard choice to determine grade of glial tumor is biopsy which is an invasive method. The purpose of this study was to investigate the role of fiber density index (FDi) by means of diffusion tensor imaging (DTI) (as a noninvasive method) in glial...

BACKGROUND Astrocytomas are the most common primary adult brain tumors. OBJECTIVES In this study, we investigated the impact of some potential prognostic factors on survival in patients with low and high grade astrocytomas. PATIENTS AND METHODS This retrospective cohort study was performed on patients with brain astrocytoma who were referred to oncology departments, Omid and Ghaem hospitals...