The major challenge to treat Parkinson’s disease (PD) is penetration of target molecule into the brain to improve the efficacy of drugs. To achieve better brain penetration and targeted delivery, 1,9-Pyrazoloanthrone (1,9-P) loaded liposomes were developed by solvent injection technique using ultrasonication and evaluated for particle size, morphology, entrapment efficiency, FT-IR, and in-vitro...

Introduction: The Iranian Brain Imaging Database (IBID) was initiated in 2017, with 5 major goals: provide researchers easy access to a neuroimaging database, provide normative quantitative measures of the brain for clinical research purposes, study the aging profile of the brain, examine the association of brain structure and function, and join the ENIGMA consortium. Many prestigious databases...

The major challenge to treat Parkinson’s disease (PD) is penetration of target molecule into the brain to improve the efficacy of drugs. To achieve better brain penetration and targeted delivery, 1,9-Pyrazoloanthrone (1,9-P) loaded liposomes were developed by solvent injection technique using ultrasonication and evaluated for particle size, morphology, entrapment efficiency, FT-IR, and in-vitro...

The co-occurrence of a brain arteriovenous malformation, Moyamoya Disease, and intracranial aneurysm is exceedingly rare. We report the third case this disease constellation, first where arises from collateral vessel. review relevant literature discuss proposed pathophysiological mechanisms clinical implications.

Phoebe Ann and Omid Jafari Pachymeningeal leptomeningeal enhancement on contrast-enhanced brain MRI come with broad differentials, including granulomatous disease of infectious or non-infectious etiology, carcinomatosis, autoimmune disorders such as vasculitis, giant cell arteritis, IgG-4 related disease.

Listeriosis is one of the CNS inflammatory diseases which is happened majority in the form of sporadic. Listeriosis is ingested with the food. Infection occurrence in an exposed person depends on the number of organisms ingested, the virulence of the organisms strain and the individual condition. It is known that Listeriosis has decisive importance as an infection which the cellular immunodefen...

Objective(s): Alternative normalization methods were proposed to solve the biased information of SPM in the study of neurodegenerative disease. The objective of this study was to determine the most suitable count normalization method for SPM analysis of a neurodegenerative disease based on the results of different count normalization methods applied on a prepared digital phantom similar to one ...

Transplants of neural tissue have been used for nearly 100 years in order to clarify the mechanisms that underlie development and regeneration of the nervous system. With reports from Sweden and Mexico that autografts of adrenal medulla produce at least transient and perhaps dramatic improve­ment in patients severly disabled by Parkinson's disease, the techniques of neural transplantation have ...

whose advice and support have been invaluable in these investigations.