The serial changes in metabolism and histology during the first 24 hours in the cold-injury trauma rat brain model were investigated by proton magnetic resonance (MR) imaging and high-resolution proton MR spectroscopy. Edema developed extensively via the corpus callosum in the ipsi- and contralateral hemispheres during observation as shown by gradually increased signal intensity on proton MR im...

background & importance: our study was performed based on the first case, reported in english, of a patient with three contemporary lesions, an extra-axial malformation and two vascular ones. case presentation: a 62-year-old man referred to our clinic due to right hand tremor associated to a slowing of idea-forming function and movements. the neuroradiological evidence showed a right fronto-tem...

background: palliative whole brain radiotherapy (wbrt) has been the standard treatment for brain metastases. ionizing radiation is known to be one of the most potent cataractogenic agents. we aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (oar) in patients with brain metastasis who undergone wbrt. materials and methods: ten conse...

traumatic brain injury (tbi) is one the most common cause of disability between young adults. these people have been socially isolated during post-surgery traumatic brain injury. in this study we investigated the effect of social isolation on the structural deficits after tbi in the young rats. young rats were divided into control group with social interaction, sham group with social isolation ...

BACKGROUND This study compared the use of static cold storage versus continuous hypothermic machine perfusion in a cohort of kidney transplant recipients at high risk for delayed graft function (DGF). METHODS In this national, multicenter, and controlled trial, 80 pairs of kidneys recovered from brain-dead deceased donors were randomized to cold storage or machine perfusion, transplanted, and...

1. Michaelis constants of goldfish brain choline acetyltransferase were found to depend on the concentration of the second substrate present and on the temperature to which the fish had been adapted. 2. Primary plots constructed from results obtained with enzyme prepared from cold-adapted or warm-adapted fish indicated that synthesis of acetylcholine took place by a sequential mechanism. 3. The...

The amygdala forms a crucial link between central pain and stress systems. Previous research indicates that psychological stress affects amygdala activity, but it is less clear how painful stressors influence subsequent amygdala functional connectivity. In the present study, we used pulsed arterial spin labeling (PASL) to investigate differences in healthy male adults' resting-state amygdala fu...