SNEDDS merupakan campuran isotropik yang terdiri dari obat, surfaktan, ko-surfaktan dan minyak. Pengembangan optimasi formulasi tepat diperlukan untuk meminimalisir waktu, biaya, serta menjamin optimal. Tujuan penulisan artikel ini adalah menjelaskan aplikasi simplex lattice design (SLD) box behnken (BBD) dalam SNEDDS. Metode digunakan menyusun review yaitu teknik studi pustaka dengan mencari l...

The stability of an emulsified liquid membrane composed of Span80 as a surfactant, D2EHPA as an extractant and sulfuric acid as an internal phase was first studied according to different diluents and many operating parameters using the Plackett-Burman design of experiments. Then the removal of methylene blue from an aqueous solution has been carried out using this emulsified liquid membrane at ...

In the present study, production of rhamnolipid biosurfactant by Pseudomonas aeruginosa OG1 was statistically optimized by response surface methodology. Box-Behnken design was applied to determine the optimal concentrations of 52, 9.2, and 4.5 g/L for carbon source (waste frying oil), nitrogen source (chicken feather peptone), and KH2PO4, respectively, in production medium. Under the optimized ...