BACKGROUND Bone density at the interradicular area plays an important role during orthodontic treatment. In view of this fact, the study was designed to quantitatively evaluate the bone density at the interradicular areas of the alveolar and basal bones of maxilla and mandible by computed tomography. METHODS One hundred and nine computed tomographic images were randomly selected, and bone den...

Identification and interpretation of pathologies in the fossil record allows for unique insights into the life histories of extinct organisms. However, the rarity of such finds limits not only the sample size for palaeopathologic studies, but also the types of analyses that may be performed. In this study, we present the first occurrence of a palaeopathology in a vertebrate from the Mesozoic of...

Osteoarthritis (OA) is characterized by alterations to subchondral bone as well as articular cartilage. Changes to bone in OA have also been identified at sites distal to the affected joint, which include increased bone volume fraction and reduced bone mineralization. Altered bone remodelling has been proposed to underlie these bone changes in OA. To investigate the molecular basis for these ch...

introduction individual x-ray diffraction patterns of biological tissues are obtained via interference of coherent scattering with their electrons. many scientists have distinguished normal and cancerous breast tissue, bone density, and urinary stone types using the x-ray diffraction patterns resulting from coherent scattering. the goal of this study was to introduce an optimized method for obt...

In biological anthropology, parameters relating to cross-sectional geometry are calculated in paired long bones evaluate the degree of lateralization anatomy and, by inference, function. Here, we describe a novel approach, newly added morphomap R package, assess distribution cortical bone along entire diaphysis. The sample comprises belonging 51 individuals (10 females and 41 males) from New Me...

Transilial bone samples were obtained at necropsy using trephine instruments with internal diameters of 2 mm and 7 mm. Undecalcified histological sections were prepared and two structural histomorphometric variables (percentage of trabecular bone volume and surface density of bone) were estimated by a Quantimet 720 image analyser. The differences between the variables measured from the two adja...

Bone mets are frequent in NSCLC. The receptor activator of Nuclear Factor κB (RANK)/ RANKL/osteoprotegerin (OPG) pathway is important bone development. EGFR signaling promotes osteoclast formation and stimulation. Understanding the biological mechanism development might have implications for treatment strategies. We studied association EGFR, RANKL, RANK, OPG gene expression tumor presence mNSCL...

background: dual-energy x-ray absorptiometry (dxa) is considered the gold standard for non-invasive measurement of bone mass. t-scores and z-scores are used to present the results of bone mass. the present study was designed to evaluate the discordance between t-scores and z-scores calculated at a same level and its relation with age, gender and body mass index (bmi) in a representative sample ...

Introduction Raman microspectroscopy (RM) is increasingly recognized as an efficient method to bring new information on the composition and structure of mineralized tissues. Physicochemical parameters (mineralization, carbonation and cristallinity) measured from RM bands provide information in bone quality changes due to aging or pathologies (1, 2, 3). In vivo models have been extensively used ...