Background The increasing longevity of the population coupled with the progress of treatments for primary tumors is enhancing the incidence and the burden of distant metastases such as bone metastases. Bone metastases are the most common cause of cancer-related pain. Quality of life may be significantly impaired as a consequence of painful bone metastases. The treatment of secondary bone lesion...

A roentgenographic scoring system was developed to help orthopaedic surgeons and bone banks estimate the quality of bone stock in proximal femoral allografts intended to use in revision arthroplasty. This system scores a standardized anteroposterior roentgenograph of the proximal femur using four indices representing morphological features of cancellous and cortical bone known to be clinically ...

Bone strength depends on the amount of bone, typically expressed as bone mineral density (BMD), determined by dual-energy X-ray absorptiometry (DXA), and on bone quality. Bone quality is a multifactorial entity including bone structural and material compositional properties. The purpose of the present study was to examine whether bone material composition properties at actively-forming trabecul...

introduction: bite wing radiographs are indicated in children with closed posterior contacts. given the fact that nowadays bitewing radiographs are taken using both paper loop and film holder, the aim of this study is the evaluation of acceptance and diagnostic quality of two methods. materials and methods: this study is a sort of diagnostic accuracy test that was performed on 20 6-8 year old c...

Smoking is a common risk factor for both chronic obstructive pulmonary disease (COPD) and osteoporosis. In patients with COPD, severe emphysema is a risk factor for vertebral fracture; however, the effects of smoking or emphysema on bone health remain largely unknown. We report bone deterioration in a mouse model of emphysema induced by nose-only cigarette smoke (CS) exposure. Unexpectedly, sho...

In the severely atrophied maxilla, implant anchorage in the zygomatic bone is considered a viable alternative to conventional dental implants with preceding bone augmentation procedures. The present microCT-based study compared the trabecular bone quality of the maxilla and zygomatic bone. MicroCT scanning was conducted in 12 halves of cadaver heads (5 male, 7 female) with edentulous, atrophied...

Atraumatic fractures of the skeleton in osteoporotic patients are directly related to a deterioration of bone strength. However, the failure of the bone tissue to withstand functional load bearing cannot be explained as a simple decrease in bone mineral density (quantity); strength is also significantly dependent upon bone quality. While a formal definition of bone quality is somewhat elusive, ...

OBJECTIVES HIV infection has been associated with reduced bone mineral density (BMD). Antiretroviral therapy (ART) has a deleterious effect on BMD, but its effect on bone fragility is not clear. The objective of this study is to analyze the BMD, microarchitecture, and tissue quality of bone in patients receiving long-term tenofovir- or abacavir-based ART. DESIGN We conducted a cross-sectional...

AIMS To assess the feasibility of training nurse practitioners to perform bone marrow aspiration and trephine biopsy, and to compare the quality of these samples with those obtained by medical staff. METHODS A retrospective audit was undertaken of nurse practitioner and medical staff performance in bone marrow procedures in a busy haematology day unit. RESULTS Nurse practitioners fared favo...