background: osteoporosis is a systemic skeletal disorder characterized by low bone mineral density (bmd) that leads to an increase in bone fragility, causing an individual to be at an increased risk for fractures. asian-indians are at an increased risk for developing osteoporosis. considering the number of asian-indians in the us is rapidly growing, they likely could be an underappreciated popu...

Our study evaluated the effects of one year-treatment with Denosumab (DB) on bone mineral density (BMD), FRAX SCORE, metabolism (MM) parameters and safety in 32-kidney transplanted patients (KTxps).

Receptor activator of NF-kappaB ligand (RANKL), produced by osteoblastic lineage cells and activated T cells, is an essential factor for osteoclast differentiation, activation, and survival. Therefore, RANKL is a focal point of therapies targeting bone diseases where there is an imbalance of bone metabolism in favor of bone resorption. The present study assesses the effects of exogenous RANKL o...

introduction: thalassemia is the most common genetic disorder, affecting around 200 million people worldwide. the etiology of this bone disease is multifactorial. seemingly, in the setting of increased bone turnover which manifests by increased bone resorption and remodeling; bone density decreases. in this research, thalassaemia patients with osteoporosis were placed on oral alendronate therap...

Lumbar spine bone mineral density and bone mineral metabolism were studied in 13 children three months or more after completion of cytotoxic chemotherapy that included ifosfamide given for different malignancies. Blood and urine were analysed for calcium, phosphorus, and magnesium and blood for alkaline phosphatase activity, parathyroid hormone, and 1,25(OH)2 vitamin D3. Bone mineral density (B...

Results As reported previously, with Micro-CT we can get better images because of the higher resolution. Micro-CT is a useful tool in defining bony morphology and the structure. Bone maturity such as distraction osteogenesis which results in increased bone mineral density (BMD) is one example of the effects of exposure to ultrasound. High BMD values are reported to increase the rate of bone agi...

INTRODUCTION Spinal cord injury (SCI) is characterized by rapid bone loss and an increased risk of fragility fracture around regions of the knee. Our purpose was to quantify changes in torsional stiffness K and strength Tult at the proximal tibia due to actual bone loss and simulated bone recovery in acute SCI. METHODS Computed tomography scans were acquired on ten subjects with acute SCI at ...

AIM To evaluate total body bone mineral density and regional bone mineral density in patients with prostate cancer with and without metastases, and to correlate them with bone scintigraphy findings. PATIENTS AND METHODS 135 patients with prostatic carcinoma and 50 healthy subjects were investigated with bone scintigraphy and dual-energy X-ray absorptiometry. The bone scintigraphic findings we...

introduction: osteoporosis is a bone disease in which there is a reduction in the amount of bone mineral content leading to an increase in the risk of bone fractures. the affected individuals not only have to go through lots of pain and suffering but this disease also results in high economic costs to the society due to a large number of fractures.  a timely and accurate diagnosis of this disea...