OBJECTIVE To examine the role of peak bone mass and subsequent postmenopausal bone loss in the development of osteoporosis and the reliability of identifying women at risk from one bone mass measurement and one biochemical assessment of the future bone loss. DESIGN Population based study. SETTING Outpatient clinic for research into osteoporosis. SUBJECTS 178 healthy early postmenopausal w...

STUDY OBJECTIVE To examine the relation between physical activity, calcium intake, and bone mineral content in children. DESIGN Population based, cross sectional study. SETTING Primary schools in Zoetermeer, The Netherlands. PARTICIPANTS Altogether 1359 Dutch boys and girls, aged 7 to 11 years (response rate 88%). MEASUREMENTS Bone mineral content was measured by quantitative roentgen m...

INTRODUCTION Genetic studies of osteoporosis have commonly examined SNPs in candidate genes or whole genome analyses, but insertions and deletions of DNA, collectively called copy number variations (CNVs), also comprise a large amount of the genetic variability between individuals. Previously, SNPs in the APC gene have been strongly associated with femoral neck and lumbar spine volumetric bone ...

OBJECTIVES The association between carbonated beverage consumption and bone mineral density was examined in a community-based cohort of older White women. METHODS One thousand women 44 to 98 years of age had bone mineral density measured at four sites and provided medical and behavioral histories, including type and quantity of carbonated beverages consumed. RESULTS Bone mineral density lev...

diabetes mellitus (dm) and osteoporosis are common diseases and their prevalence increases with age. several investigations have indicated that type 1 dm has a significant relationship with bone loss, whereas in type 2 diabetes, this relationship is controversial. therefore, this study was conducted to determine the relationship between osteoporosis and type 2 dm in elderly people. this populat...

background: thalassemia is the most common hereditary anemia and beta thalassemia major is its most severe form. endocrine abnormalities in thalassemia major are common disturbing complications that need prompt management. the purpose of this study was to determine the endocrine disorders and bone mineral density in patients with major -thalassemia in qazvin, iran. methods: in this cross- secti...

background: low bone mass is a frequent complication of chronic inflammatory disease. the pathogenesis of osteoporosis in chronic inflammatory disease may be secondary to releases of cytokines such as tnf-a and il6. chronic gastritis due to helicobacter pylori (hp) infection may lead to decreased bone mineral density (bmd) and predispose patients to osteoporosis. the objective of this study was...

objective: osteoporosis is the most common metabolic disease of the bone decreasing bone mineral density (bmd) particularly in postmenopausal women. on the other hand, panoramic radiography has several applications in dentistry. it appears that by calculating some indices on panoramic radiographs, we may be able to predict the risk of osteoporosis in high-risk individuals. the present study was...

Background: Thalassemia is the most common hereditary anemia and beta thalassemia major is its most severe form. Endocrine abnormalities in thalassemia major are common disturbing complications that need prompt management. The purpose of this study was to determine the endocrine disorders and bone mineral density in patients with major -thalassemia in Qazvin, Iran. Methods: In this cross- sect...

Introduction: Numerous factors are considered to determine human bone quality. Particularly, volumetrically evaluated bone mineral density (DXABMD) as well as the mechanical properties of bone samples serve to assess fracture risks. However, the differentiation and degree of mineral content and/or morphology effects on bone toughness remained to a large extent unanswered due to large measuring ...