نتایج جستجو برای: bone biomarkers

تعداد نتایج: 402955  

2018
Marissa M Shams-White Mei Chung Zhuxuan Fu Karl L Insogna Micaela C Karlsen Meryl S LeBoff Sue A Shapses Joachim Sackey Jian Shi Taylor C Wallace Connie M Weaver

BACKGROUND Protein may have both beneficial and detrimental effects on bone health depending on a variety of factors, including protein source. OBJECTIVE The aim was to conduct a systematic review and meta-analysis evaluating the effects of animal versus plant protein intake on bone mineral density (BMD), bone mineral content (BMC) and select bone biomarkers in healthy adults. METHODS Searc...

2009
Jennifer Weuve Susan A. Korrick Marc A. Weisskopf Louise M. Ryan Joel Schwartz Huiling Nie Francine Grodstein Howard Hu

BACKGROUND Recent data indicate that chronic low-level exposure to lead is associated with accelerated declines in cognition in older age, but this has not been examined in women. OBJECTIVE We examined biomarkers of lead exposure in relation to performance on a battery of cognitive tests among older women. METHODS Patella and tibia bone lead--measures of cumulative exposure over many years-...

2016
Jules A. Westbrook David A. Cairns Jianhe Peng Valerie Speirs Andrew M. Hanby Ingunn Holen Steven L. Wood Penelope D. Ottewell Helen Marshall Rosamonde E. Banks Peter J. Selby Robert E. Coleman Janet E. Brown

BACKGROUND Bone is the predominant site of metastasis from breast cancer, and recent trials have demonstrated that adjuvant bisphosphonate therapy can reduce bone metastasis development and improve survival. There is an unmet need for prognostic and predictive biomarkers so that therapy can be appropriately targeted. METHODS Potential biomarkers for bone metastasis were identified using prote...

Journal: :Journal of medicinal food 2015
Marcus L Elam Sarah A Johnson Shirin Hooshmand Rafaela G Feresin Mark E Payton Jennifer Gu Bahram H Arjmandi

Menopause leads to an increased risk for osteoporosis in women. Although drug therapies exist, increasing numbers of people prefer alternative therapies such as dietary supplements, for example, calcium, vitamin D, and collagen hydrolysates for the prevention and treatment of osteoporosis. We have previously shown that a 3-month intervention using a calcium-collagen chelate (CC) dietary supplem...

2017
Hansongyi Lee Ryowon Choue Hyunjung Lim

BACKGROUND/OBJECTIVES Soy isoflavones are expected to improve menopausal symptoms and osteoporosis in women. However, their efficacy is still inconclusive, and there was limited data for postmenopausal women in South Korea. We examined the effects of soy isoflavones on climacteric symptoms, bone biomarkers, and quality of life in Korean postmenopausal women. SUBJECTS/METHODS A randomized, dou...

Journal: :Stem cell research 2015
Yang Hoon Huh Minsoo Noh Frank R Burden Jennifer C Chen David A Winkler James L Sherley

There is a long-standing unmet clinical need for biomarkers with high specificity for distributed stem cells (DSCs) in tissues, or for use in diagnostic and therapeutic cell preparations (e.g., bone marrow). Although DSCs are essential for tissue maintenance and repair, accurate determination of their numbers for medical applications has been problematic. Previous searches for biomarkers expres...

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