To save layout area for electrostatic discharge (ESD) protection design in the SOC era, test chip with large size NMOS devices placed under bond pads has been fabricated in 0.35-μm one-poly-four-metal (1P4M) 3.3V CMOS process for verification. The bond pads had been drawn with different layout patterns on the inter-layer metals to investigate the effect of bonding stress on the active devices u...

How thermally activated structural excitations quantitatively mediate transport and microplasticity in a model binary glass at the microsecond timescale is revealed using atomistic simulation. These local excitations, involving stringlike sequence of atomic displacements, admit far-field shear-stress signature underlie free-volume bond geometry. Such found to correspond evolution disclination n...

States of self stress, organizations of internal forces in many-body systems that are in equilibrium with an absence of external forces, can be thought of as the constitutive building blocks of the elastic response of a material. In overconstrained disordered packings they have a natural mathematical correspondence with the zero-energy vibrational modes in underconstrained systems. While substa...

strength, flexural modulus, and contraction stress of one orthodontic composite and two flowable composites. Orthodontic brackets were bonded to 45 human maxillary premolars with the composites Transbond XT, Filtek Z-350 flow and Opallis flow and tested for shear bond strength. For measurement of flexural strength and flexural modulus, specimens were fabricated and tested under flexion. For the...

Prolyl hydroxylase domain protein 2 (PHD2) belongs to an evolutionarily conserved superfamily of 2-oxoglutarate and Fe(II)-dependent dioxygenases that mediates homeostatic responses to oxygen deprivation by mediating hypoxia-inducible factor-1α (HIF-1α) hydroxylation and degradation. Although oxidative stress contributes to the inactivation of PHD2, the precise molecular mechanism of PHD2 inact...