Background. Antibiotic exposure and specimen volume are known to affect pathogen detection by culture. Here we assess their effects on bacterial pathogen detection by both culture and polymerase chain reaction (PCR) in children. Methods. PERCH (Pneumonia Etiology Research for Child Health) is a case-control study of pneumonia in children aged 1-59 months investigating pathogens in blood, naso...

We discuss the rise of a liquid inside an angular capillary tube. It is shown that for a wetting liquid, the height of the rise is (as usually) inversely proportional to the length which characterizes the confinement. The exact laws deduced from energetic considerations are found to be in excellent agreement with the data. We then show how such tubes can be used to prevent bubbles from being tr...

McLawhon RW. Absorption of therapeutic drugs by barrier gels in serum separator blood collection tubes: volume-and time-dependent reduction in total and free drug concentrations.

Electrophoretic separations carried out in capillary tubes offer the possibilities of rapid and automated analyses of small volumes of complex mixtures with unprecedented resolution and sensitivity. Some emerging developments of this new instrumentation are reviewed.

In a study of collodion membranes which had been coated with films of gelatin or egg albumin, it was found that the presence of the protein reduced the rate of flow of water through the membranes, as would be expected if the protein film were formed on the wails of the pores. ~ In order to determine the thickness of such films, an at tempt has been made to estimate the size of pores in membrane...

An efficient photochemical method for the site-specific immobilization and patterning of (bio)molecules inside glass capillary tubes is reported. The strategy involves the photodeprotection of reactive aminooxy groups on surfaces and subsequent reaction with aldehyde containing (bio)molecules.

The purpose of this study was to investigate the influence of heat transfer on measured thermal inactivation kinetic parameters of bacteria in solid foods when using tube methods. The bacterial strain selected for this study, Escherichia coli K-12, had demonstrated typical first-order inactivation characteristics under isothermal test conditions. Three tubes of different sizes (3, 13, and 20 mm...

We report the demonstration of compact fluidic fibre lasers based on capillary tubes and photonic crystal fibres, featuring single channel and multiple laterally integrated fluidic lasers respectively. Their preparation was based on capillary action and lasing occurred without the need for external mirrors or lithographically defined microstructures. The fibre lasers were found to be tunable by...

We detail the technique, procedure, and equipment required to properly obtain a micro-scale capillary (fingerstick) blood specimen for subsequent determination of its lead content. We divide the microsampling procedure into preparation of sampling equipment and subject, the fingerstick, micro blood collection devices, and transport and storage. The concept of a total-system approach to qualityc...