BACKGROUND Phthalates are ubiquitous in the environment, but concentrations in multiple media from breast-feeding U.S. women have not been evaluated. OBJECTIVES The objective of this study was to accurately measure and compare the concentrations of oxidative monoester phthalate metabolites in milk and surrogate fluids (serum, saliva, and urine) of 33 lactating North Carolina women. METHODS ...

Sulfobromophthalein (BSP) is normally cleared from the blood by the liver and excreted into the bile. Brauer, Krebs and Pessotti (1) originally reported that part of the pigment appearing in dog bile was chromatographically different from the injected dye. Our studies using differenlt chromatographic techniques indicate that in man the bulk of the recovered pigments (65 to 75 per cent, accordin...

To evaluate the effects of treating or supplementing common reed (Phragmites australis) with 2% urea on intake, nutrient apparent digestibility, and blood metabolites, fifteen Baluchi rams (35.4±2.3 kg body weight) were used in a completely randomized design. Treatments were as follows: 1) common reed, 2) common reed supplemented with 2% urea solution at feeding, and 3) common reed tre...

Patients and animals with chronic kidney disease (CKD) exhibit profound alterations in the gut environment including shifts in microbial composition, increased fecal pH, and increased blood levels of gut microbe-derived metabolites (xenometabolites). The fermentable dietary fiber high amylose maize-resistant starch type 2 (HAMRS2) has been shown to alter the gut milieu and in CKD rat models lea...

Abstract After decades of research on non-invasive glucose monitoring, invasive devices based finger blood sampling are still the predominant reference for diabetic patients accurately measuring levels. Meanwhile, continues improving point-of-care technology toward development painless and more accurate devices. Raman spectroscopy is well-known as a potentially valuable approach However, previo...

The objective of the study, therefore, is to review and package the current reference values of some haemotological and serum biochemical of indigenous pastoral cattle in tropical Africa. Haematological investigation has gained a global popularity as a prime diagnostic and management tool in veterinary practice. It ascertains the physiological, nutritional and pathological status of an animal a...

Lidocaine is a frequently administered anti-arrhythmic drug, particularly useful in emergency situations because of its rapid onset of action (1). Therapeutic drug monitoring of lidocaine is recommended because of its potent central nervous system toxicity. Moreover, lidocaine has been implicated in numerous accidental and homicidal deaths (2). Thus its chemical stability in patients’ specimens...

BACKGROUND Carbamazepine (CBZ) occasionally causes haematological disorders such as thrombocytopenia, and recently a case of oxcarbazepine (OXCBZ)-induced thrombocytopenia has been described. The aim of our study was blood platelet count determination in epileptic patients treated with CBZ and OXCBZ, and its relationship with the dose and serum levels of these drugs and its metabolites. METHO...