objective: the effect of herbal medicine is more useful than synthetic medicines. the present research paper aims to show the effects of leaves extracts of zizyphus spina christi (zsc) on lipid profile, lipid peroxidation and activities of aminotransferase enzymes in streptozocin induced diabetic adult male rats. materials and methods: fifty six male rats weighing 150-200 gm were included in th...

We investigated lipid peroxidation, resistance of plasma and red blood cells to oxidation, and antioxidant defense system in erythrocytes and sera in patients with type 2 diabetes mellitus. One group included newly diagnosed 20 patients and the other included 20 patients treated with oral antidiabetic agents (OAD). Twenty healthy subjects served as controls. Serum and red blood cell malondialde...

In hepatic iron overload, iron-catalyzed lipid peroxidation has been implicated in the mechanisms of hepatocellular injury. Lipid peroxidation may produce reactive aldehydes such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), which may form aldehyde-protein adducts. We investigated whether lipid peroxidation occurred in rats fed a diet containing 3% carbonyl iron for 5-13 wk, and if thi...

background : methamphetamine (ma) is an illegal amphetamine-like which stimulate the central nervous system. in recent years, ma has been widely abused worldwide. previous studies have suggested that oxidative stress (os) plays an important role in ma-induced toxicity. from this view, antioxidant therapy could be considered as a potential drug therapy in ma abusers. therefore, the objective of ...

The present study was designed to determine whether lipid peroxidation was associated with the impairment of the fertilizing capability of gilthead sperm after acute exposure to anionic surfactant Sodium Dodecyl Sulphate (SDS). Spawned eggs and sperm were collected from adult giltheads. Sperm suspensions (100,000,000 spermatozoa/mL) were dosed separately with different concentrations of SDS (0....

Sepsis and septic shock are are among the major causes of mortality in intensive care units. The lung and kidney are the organs most affected by sepsis. Evidence exists that lipid peroxidation and apoptosis may be responsible for the high mortality due to sepsis. Ischemic preconditioning (IP) is a method for the protection of tissues and organs against ischemia/reperfusion injury by reducing re...

background: the lipid peroxides and their degradation products are highly toxic to spermatozoa and may play a major role in sperm dysfunction. the purpose of this study was to determine the level of lipid peroxidation as indicated by malondialdehyde (mda) in the spermatozoa and seminal plasma of asthenozoospermic and normozoospermic males. in addition, correlation of lipid peroxidation with mot...

Aims: To assess and compare the body mass index (BMI), serum leptin, and lipid peroxidation represented by serum malondialdehyde (MDA) levels in epileptic patients on valproate (VPA) and topiramate (TPM) monotherapy for at least 6 months taking in consideration dosage and duration of therapy, in comparison to healthy controls. Methods: A cross-sectional, case-series study design was adopted, fo...

The present study was carried out on mongrel dogs. Haemorrhagic shock of different severities and duration was produced by exsanguination from an artery. After the required duration of shock, two third of the volume of blood withdrawn was transfused back into the animal. Effect of haemorrhage and reperfusion of blood after haemorrhagic shock on lipid peroxidation was assessed by measuring plasm...