BACKGROUND Increasing blood supply safety is one of the most important goals of blood services in the world. In this study, we reviewed the prevalence rate and the trends of three main infections in whole blood donations and strategies for improving blood safety in Yazd blood transfusion center, Iran. MATERIALS AND METHODS In this cross sectional study, data on hepatitis B, C and HIV infectio...

Preliminary work on the development of measures appropriate for the safety domain is reported. Measures are expressed in the style of the Practical Software and Systems Measurement (PSM) approach, a programme sponsored by the US DoD. Proposed measures are integrated with the PSM measurement framework. Reported work has been informed by discussions within the PSM community and by concurrent work...

Background: In the present study the amount of requested blood products in major departments of Imam Reza Medical Center, Kermanshah, Iran has been studied to evaluate the necessity of these requests and also the amount of blood products wastage because of unnecessary requests. Materials and Methods: In the present study the information related to 4832 unit of requested blood products from Ira...

Safety cases offer a means for communicating information about the system safety among the system stakeholders. Recently, the requirement for a safety case has been considered by regulators for safety-critical systems. Adopting safety cases is necessarily dependent on the value added for regulatory authorities. In this work, we outline a structured approach for assessing the level of sufficienc...

Hemovigilance is used to track and reduce the occurrence of adverse events associated with blood donations (1). Hemovigilance programs have now been in existence for about 20 years after being developed in 1993 in France. Although it has emerged as a tool to improve transfusion safety, many countries and centers are still in the development stage and have not yet established functioning hemovig...

Background: The transmission of pathogens via blood transfusion is still a major threat. Expert conferences established the need for a pro-active approach and concluded that the introduction of a pathogen inactivation/reduction technology requires a thorough safety profile, a comprehensive pre-clinical and clinical development and an ongoing hemovigilance program. Material and Methods: The INTE...

Since November 2015, Puerto Rico has reported active mosquito-borne transmission of Zika virus. Because of the potential for Zika virus to be transmitted through transfusion of blood components, and because a high percentage of persons infected with Zika virus are asymptomatic, the Food and Drug Administration (FDA) recommended that blood collections cease in areas of the United States affected...

BACKGROUND Blood transfusion is always associated with some level of risk. Haemovigilance is a risk monitoring system integral to the practice of transfusion medicine whose ultimate purpose is to improve the quality and safety of transfusion therapy. OBJECTIVE To examine the contribution of haemovigilance to blood safety, including the approaches that some countries have taken to institute ha...

BACKGROUND: The transmission of pathogens via blood transfusion is still a major threat. Expert conferences established the need for a pro-active approach and concluded that the introduction of a pathogen inactivation/reduction technology requires a thorough safety profile, a comprehensive pre-clinical and clinical development and an ongoing hemovigilance program. MATERIAL AND METHODS: The INTE...