Chemoprophylaxis Vaccination (CVac) confers long lasting sterile protection against homologous parasite strains in humans, and involves inoculation of infectious sporozoites (SPZ) under drug cover. CVac using the drug chloroquine (CQ) induces pre-erythrocytic immunity in humans that includes antibody to SPZ and T-cell responses to liver stage (LS) parasites. The mechanism by which CVac with CQ ...

  Toxoplasma gondii an intracellular parasite infected large proportion of the world population, but mostly without visible clinical signs in immunocompetent patients. The present study was performed to determined levels cytokines (IL-12 , IFN-γ) and human proflin-1 (PFN-1) sera 125 aborted women as case group 30 healthy (15 non pregnant 15 women) control groups Women's children Hospital A...

Basic information is given with evaluation of views on further research. Illustrations include original drawings, photographs, sequence studies, and electron photomicrographs. Characteristics are examined of the protistan agents, and principles governing maintenance, perpetuation, and diseasecausing abilities. Some 19 contributors "assist in over-coming the amputation of microbiology into the v...

OBJECTIVES Little is known about blood cholesterol (blood-C) levels under conditions of infection and limited diet. This study examines blood-C and markers of infection and inflammation in the Tsimane of the Bolivian Amazon, indigenous forager farmers living in conditions that model preindustrial European populations by their short life expectancy, high load of infections and inflammation, and ...

Cardiac involvement represents the main cause of mortality among patients with Chagas disease, and the relevance of trypanocidal treatment to improving diastolic dysfunction is still doubtful. In the present study, we used a canine model infected with the benznidazole-sensitive Berenice-78 Trypanosoma cruzi strain to verify the efficacy of an etiologic treatment in reducing the parasite load an...

The inhibitory effect of an antiserum to surface protein P50 of Babesia gibsoni on the growth of the parasite was determined with severe combined immunodeficiency mice given canine red blood cells. The antiserum to the recombinant P50 protein significantly inhibited the parasite growth, indicating that P50 might be a useful vaccine candidate.

We report 74 patients in Italy infected with Mansonella perstans nematodes, a poorly described filarial parasite. M. perstans nematodes should be included in the differential diagnosis for patients with eosinophilia from disease-endemic countries. Serologic analysis is useful for screening, and testing for microfilaremia in peripheral blood should be performed for parasite-positive patients.

In vitro lymphocyte responses of high responder (HR) and low responder (LR) guinea pigs from pe-ripheral blood lymphocytes (PBL) to parasite antigens soluble protein third stage larvae (SPL3) and soluble protein adult stage ( SPA), non-parasite antigen ovalbumin (OVA) were examined. There was substantial differences between HR and LR guinea pigs in the rate of acquisition of responsiveness to t...

Combination of seven surveys of blood parasites in North American passerines reveals weak, highly significant association over species between incidence of chronic blood infections (five genera of protozoa and one nematode) and striking display (three characters: male "brightness," female "brightness," and male song). This result conforms to a model of sexual selection in which (i) coadaptation...

IT has been shown by numerous observers that plasmochin combined with quinine is far more effective in subtertian malaria than quinine alone. In the present paper I propose to offer a rational explanation for these observed facts, and to quote further cases in support of these observations. That quinine has very, little effect, if any, in destroying the crescentic gametocytes of 1\ falciparum i...