PURPOSE The purpose of this study was to evaluate the effect of alendronates on bone remodeling around titanium implant in the maxilla of rats. MATERIALS AND METHODS The maxillary first molars were extracted and customized-titanium implants were placed immediately in thirty male Sprague-Dawley rats. The rats were divided into experimental (bisphosphonate) group and control group. At 4 weeks a...

Background Reduction of orthodontic treatment time is a major concern for orthodontists. Low level laser therapy (LLL) has been widely used in dentistry and it has been claimed that it could stimulate bone formation. Objective The aim of the present study was to evaluate histological effects of LLL on alveolar bone remodeling during experimental tooth movement in rabbits. Methods In this ex...

Excessive activity of osteoclasts becomes manifest in many common lytic bone disorders such as osteoporosis, Paget's disease, bone aseptic loosening and tumor-induced bone destruction. Vacuolar proton pump H+-adenosine triphosphatases (V-ATPases), located on the bone-apposed plasma membrane of the osteoclast, are imperative for the function of osteoclasts, and thus are a potential molecular tar...

The formation of new bone involves both the deposition of bone matrix, and the formation of a network of cells embedded within the bone matrix, called osteocytes. Osteocytes derive from bone-synthesising cells (osteoblasts) that become buried in bone matrix during bone deposition. The generation of osteocytes is a complex process that remains incompletely understood. Whilst osteoblast burial de...

RESUMO: O artigo discute um dos temas poucos debatidos na educação, porém extremamente necessário para o processo educacional. Os espaços escolares historicamente não são valorizados mesma proporção da importância que eles possuem. A infraestrutura escolar ficou ainda mais importante após a lei Reforma do Ensino Médio dentre as tantas mudanças aumenta carga horária nas escolas. alunos passam te...

Obesity, a global problem, is a multifactorial disorder. The factors are environmental, metabolic and genetic and their interaction with each other regulates the body weight. Imbalance in either of the factors may be responsible for weight gain. With advancement of research techniques in the last decade, genetic studies have been undertaken for several different causative mutations involving ob...

Web apps are built by using a combination of HTML, CSS, and JavaScript. While building modern web apps, it is common practice to make use third-party libraries frameworks, as improve developers’ productivity code quality. Alongside these benefits, the adoption such results in introduction JavaScrip...

OBJECTIVE To investigate the feasibility of the complex of the fibrin sealant (FS) and the bone marrow mesenchymal stem cells(MSCs) to create a new cartilage in the nude mice by the issue engineering technique. METHODS The MSCs were isolated from healthy humans and were expanded in vitro. And then the MSCs were induced by the defined medium containing the transforming growth factor beta1 (TGF...