Background: Thalassemia syndromes are the most common genetic disorders in the world. They happen due to genetic defects in process of haemoglobin synthesis, and would be classified to many groups mainly α and β, based on the kind of defect. Anemia is the main clinical manifestation of this phenotype of disorder. In order to correct the chronic anemia in thalassaemic individuals, they may need ...

Avermectins are powerful endectocides with an established potential to reduce the incidence of vector-borne diseases. Here, we show that several avermectins inhibit the hepatic stage of Plasmodium infection in vitro Notably, ivermectin potently inhibits liver infection in vivo by impairing parasite development inside hepatocytes. This impairment has a clear impact on the ensuing blood stage par...

Tick-borne fever (TBF) is caused by the rickettsiae Ehrlichia phagocytophila and is a common disease in sheep in tick (Ixodes ricinus) infested areas in Norway. Earlier investigations have shown that some sheep could remain infected for several months after the primary infection. In this study, the persistence of E. phagocytophila after experimental infection was investigated in 2 age groups of...

Ehrlichioses are important emerging zoonotic tick-borne diseases that can affect both animals and humans. Clinical manifestations of ehrlichiosis caused by different members of Anaplasmataceae in dogs are similar to each other and to other diseases showing systemic manifestation. The observation of inclusions in white blood cells and in platelets cannot be used to confirm the Anaplasmataceae et...

Ovine anaplasmosis is a tick-borne rickettsial disease, widespread in tropical and subtropical areas. In the present study, a PCR-RFLP method based on major surface protein 4 (MSP4) gene, was utilized for the detection of Anaplasma infection in 119 sheep blood samples collected from different parts of Ahvaz in the southwest of Iran. PCR identified Anaplasma infections in 87.4% (104/119) of the ...

background: intravenous drug users (ivdus) who share needles/syringes and practice sexual behaviors, are the most important group in the transmission of blood-borne infection diseases such as hepatitis c virus (hcv). therefore identification of prevalent high-risky behaviors among ivdus to detect the most route of transmission among them is essential to develop harm reduction programs among ivd...

Background: Intestinal protozoa transmitted by food are the most common opportunistic parasites among the HIV+/AIDS patients. As, there is no report about prevalence of food-borne intestinal parasites in such patients in Yazd, so this study was performed to determine the prevalence of intestinal protozoa in the HIV+/AIDS patients in comparison with HIV- individuals. Methods: A case-control stu...

background essential oils (eos) possess antibacterial properties and represent a natural source to treat infections and prevent food spoilage. their chemical composition might be affected by the environmental condition and the developmental growth stages of the plant. objectives the current study aimed to determine the variations in chemical compositions and antimicrobial activities of the eos ...

While the risk of infection through occupational exposure to blood-borne viruses is a major concern of dental health care workers, the National HIV/AIDS Strategy and many health, AIDS and discrimination-related agencies have identified discrimination related to HIV/AIDS as a priority area for action. In 1995 the Commonwealth Department of Health and Family Services selected the School of Medica...