نتایج جستجو برای: blocking antibodies
تعداد نتایج: 206867 فیلتر نتایج به سال:
The ongoing pandemic of coronavirus disease (COVID-19) stimulated an unprecedented international collaborative effort for rapid diagnosis, epidemiologic surveillance, clinical management, prevention, and treatment. This review focuses on the current new therapeutical approaches, summarizing viral structure life cycle, with emphasis specific steps that can be interfered by antivirals: (a) inhibi...
AIM The aim of this study was to determine whether innate immune signalling influences the vascular repair process in response to mechanical injury of arteries in mice. METHODS AND RESULTS A non-obstructive collar was introduced around the carotid artery of MyD88-deficient mice, and neointima formation was compared with that observed in MyD88-competent mice. MyD88-deficient mice are character...
Critical contribution of CD80 and CD86 to induction of anterior chamber-associated immune deviation.
Intraocular inoculation of antigens induces anterior chamber-associated immune deviation (ACAID), which is mediated by development of regulatory T cells in response to antigen-presenting cells (APC) pre-conditioned by intraocular transforming growth factor-beta (TGF-beta). In this study, we examined the involvement of T-cell co-stimulatory molecules in this process. To mimic the intraocular APC...
24 Mucosal epithelial cell surface galactosylceramide (Galcer) has been postulated to be a receptor 25 for HIV-1 envelope (Env) interacting with mucosal epithelial cells. Disruption of HIV-1 Env 26 interaction with such alternate receptors could be one strategy to prevent HIV-1 entry through 27 the mucosal barrier. To study antibody modulation of HIV-1 Env-Galcer interactions, we have 28 used G...
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