Electrochemical sensors and biosensors based on inhibition are sensitive methods to determine the concentration of toxic substances in environment and clinic applications. Heavy metal cations bind to biological molecules and inactive important enzyme systems, such as acetylcholinesterase (AChE). In this paper, the amperometric sensors and biosensors based on AChE inhibition were developed using...

The magnetoelastic (ME) biosensors are used to detect pathogen in fresh juice or milk by solenoid coil, and also developed for real-time, direct pathogen detection on food surfaces by surface-scanning coil. This paper presents blocking effect of different reagents on non-specific binding for detecting Salmonella typhimurium in apple juice using phage-based magnetoelastic biosensors. Three diffe...

Guided-wave optical biosensors are reviewed in this paper. Advantages related to optical technologies are presented and integrated architectures are investigated in detail. Main classes of bio receptors and the most attractive optical transduction mechanisms are discussed. The possibility to use Mach-Zehnder and Young interferometers, microdisk and microring resonators, surface plasmon resonanc...

A model of an action of the amperometric biosensors based on carbon paste electrodes encrusted with single microreactor is analyzed. The model is based on non stationary diffusion equations containing non-linear term related to the enzymatic reaction. The biosensors current, which is a function of the concentration gradient of the reaction product on the electrodes, is used for analyzing of dyn...

Whole-cell biosensors are a good alternative to enzyme-based biosensors since they offer the benefits of low cost and improved stability. In recent years, live cells have been employed as biosensors for a wide range of targets. In this review, we will focus on the use of microorganisms that are genetically modified with the desirable outputs in order to improve the biosensor performance. Differ...

Abstarct It was analyzed number of biosensors intended for the determination of total toxicity of some objects of the environment. To control of total toxicity of the environment it was proposed biosensors based on the measurement of bioluminescence of bacteria (Vibrio fisheri and Ph. Phosphoreum) as well as on the estimation of the level of chemiluminescence of Daphnia magna living medium. The...

Nanomaterials and nanostructures exhibit unique size-tunable and shape-dependent physicochemical properties that are different from those of bulk materials. Advances of nanomaterials and nanostructures open a new door to develop various novel biosensors. The present work has reviewed the recent progress in electrochemical, surface plasmon resonance (SPR), surface-enhanced Raman scattering (SERS...

Genetically encoded biosensors allow the noninvasive imaging of specific biochemical or biorecognition processes with the preservation of subcellular spatial and temporal information. Aequorea green fluorescent protein (FP) and its engineered variants are a critical component of genetically encoded biosensors, as they serve to provide a 'read-out' of the biorecognition event under investigation...

Biosensors based on Förster Resonance Energy Transfer (FRET) between fluorescent protein mutants have started to revolutionize physiology and biochemistry. However, many types of FRET biosensors show relatively small FRET changes, making measurements with these probes challenging when used under sub-optimal experimental conditions. Thus, a major effort in the field currently lies in designing n...

Recharging implantable electronics from the outside of the human body is very important for applications such as implantable biosensors and other implantable electronics. In this paper, a recharging method for implantable biosensors based on a wearable incoherent light source has been proposed and simulated. Firstly, we develop a model of the incoherent light source and a multi-layer model of s...