Hydrosilylation of alkenes with epoxide-terminated tri(ethylene oxide) moieties on Si-H surfaces yields homogeneous monolayers for the efficient coupling of biomolecules. The wetting properties of the epoxide-functionalized surface allow for the spotting of solutions of biomolecules, making the surface amenable to microarraying. Immobilization of thiolated DNA was achieved in a single step to f...

This work aims at developping a multidisciplinary approach to highlight the correlation between the toxicity of alumina engineered nanoparticles (NP) and their physicochemical characteristics. Accuracy of measurements depends on cell production after contact with particles, but also depends on the ability of biomolecules to get adsorbed on the NP [1]. That’s why, mechanisms of biomolecules adso...

Glucose and cholesterol are biomolecules of prime importance to human life as they are associated with a number of diseases such as diabetes, cardiac diseases, kidney failure, etc. Quantitative determination of these biomolecules is very important in biochemistry, clinical chemistry and food biology. Numerous methods such as spectrometry, amperometry, HPLC, polarometry, and capillary electropho...