Functional surfaces with biomimetic nanotexture have aroused much interest because of their great advantages in applications. The nanometer-sized biomimetic textures are fabricated using current induced local anodic oxide (LAO) method. By controlling pulsed bias voltage, pulsewidth and relative humidity, the dimensions of biomimetic textures can be precisely controlled. In our study, an atomic ...

Microtubules are self-assembling biological nanotubes that are essential for cell motility, cell division and intracellular trafficking. Microtubules have outstanding mechanical properties, combining high resilience and stiffness. Such a combination allows microtubules to accomplish multiple cellular functions and makes them interesting for material sciences. We review recent experiments that e...

When a piece of tracing paper is placed gently on the surface of a bath of water, it rapidly curls up from one edge and rolls up due to the swelling of the side in contact with water. With time, as the swelling front propagates through the thickness of the paper, the paper gradually uncurls itself and eventually straightens out. We analyze the experimental dynamics of rolling and unrolling of t...

Iron transport into the cells of microbes is mediated by low— molecular—weight sequestering agents (siderophores) which are powerful and highly specific sequestering agents for Fe(III). The current status of iron uptake by E. coli as mediated by the tricatechol siderophore entero— bactin will be reviewed. Recently the synthesis of kinetically inert Rh(III) complexes of enterobactin analogs have...

Cyclic alkenyl triflates are useful intermediates in organic synthesis usually synthesized from ketones through a reaction involving enolization and trapping with a triflating agent. This sequence suffers from some stereochemical drawbacks owing to the basic conditions required. Herein, we describe a new acid-mediated cationic cyclization reaction of enyne derivatives (or alkynols) to access cy...

(4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane. Each step proceeded in moderate-to-excellent yields and the overall yield across five steps 28%. The compound identified characterized by 1H 13C{1H} NMR, high-resolution mass spectroscopy, elemental analysis. This its derivatives have pote...

Hydroxyapatite (HAp) is the emerging most bioceramic, which is widely used in various biomedical applications, mainly in orthopedics and dentistry due to its close similarities with inorganic mineral component of bone and teeth. Synthetic HAp is known to be similar to naturally occurring HAp on the basis of crystallographic and chemical studies. Several methodologies have been investigated and ...

Propylthiouracil (PTU) and methimazole (MMI) are the most commonly used antithyroid drugs. The available data suggest that these drugs may block the thyroid hormone synthesis by inhibiting the thyroid peroxidase (TPO) or diverting oxidized iodides away from thyroglobulin. It is also known that PTU inhibits the selenocysteine-containing enzyme ID-1 by reacting with the selenenyl iodide intermedi...

The first cyclopenta[b]benzofuran derivative, rocaglamide, from Aglaia elliptifolia, was found to exhibit considerable insecticidal activities and excellent potential as a therapeutic agent candidate in cancer chemotherapy; the genus Aglaia has been subjected to further investigation. Both the structural complexity of rocaglamide and its significant activity make it an attractive synthetic targ...

Propylthiouracil (PTU) and methimazole (MMI) are the most commonly used antithyroid drugs. The available data suggest that these drugs may block the thyroid hormone synthesis by inhibiting the thyroid peroxidase (TPO) or diverting oxidized iodides away from thyroglobulin. It is also known that PTU inhibits the selenocysteine-containing enzyme ID-1 by reacting with the selenenyl iodide intermedi...