background: dielectric barrier discharge (dbd), a source of non-thermal plasma, is used in surface decontamination. objective: to study the effect of dbd plasma treatment, we evaluated the effect of plasma exposure time on inactivation of bacillus subtilis. results: applying the dbd plasma to the culture of b. subtilis caused complete sterilization of the surface without any thermal effects. in...

Here we present the successful translation of a pore size distribution (PSD) estimation method from NMR to MRI. This approach is validated using a well-characterized MRI phantom consisting of stacked glass capillary arrays (GCA) having different diameters. By employing a double pulsed-field gradient (d-PFG) MRI sequence, this method overcomes several important theoretical and experimental limit...

Both (19)F MRI and optical imaging are powerful noninvasive molecular imaging modalities in biomedical applications. To integrate these two complementary imaging modalities, the design and synthesis of a novel (19)F MRI/fluorescence dual-modal imaging agent is reported herein. Through Sonogashira coupling reaction between the fluorinated phenylacetylene and 1,2,4,5-tetraiodobenzene, a fluoropho...

The major challenge with classifying high dimensional biomedical data is in identifying the appropriate feature representation to (a) overcome the curse of dimensionality, and (b) facilitate separation between the data classes. Another challenge is to integrate information from two disparate modalities, possibly existing in different dimensional spaces, for improved classification. In this pape...

Aizu Research Cluster for Medical Engineering and Informatics, Center for Advanced Information Science and Technology,The University of Aizu, Aizu-Wakamatsu, Fukushima 965-8580, Japan The theme of this special issue (supplement) is “Current Challenging Medical Image Analysis”. This issue consists of two selected papers presented at the 35 IEEE-EMBC Workshop on Current Challenging Image Analysis...

ABSTRACT Measurement of breast tissue response to external stimulation has the potential to unveil additional dynamic biomarkers of disease states. Recently tumor contrast generated by breathing-gas induced vascular changes has been demonstrated using both BOLD imaging [1] and MRIguided near infrared diffuse optical tomography [2]. At the same time, in the biomedical optics community, temporall...

BACKGROUND The purpose of this meta-analysis was to evaluate the diagnostic accuracy of perfusion magnetic resonance imaging (MRI) as a method for differentiating glioma recurrence from pseudoprogression. METHODS The PubMed, Embase, Cochrane Library, and Chinese Biomedical databases were searched comprehensively for relevant studies up to August 3, 2016 according to specific inclusion and exc...

INTRODUCTION We are developing a new diagnostic technology: magnetic resonance imaging (MRI) and spectroscopy of hyperpolarized noble gases. Large non-equilibrium nuclear spin polarizations can be created in the spin-1/2 noble gases, He and Xe, using the technique of spin-exchange optical pumping. Such large polarizations greatly enhance the magnetic resonance detection of He and Xe, enabling h...

High-resolution and quantitative MRI are prone to various types of artifacts, which make it challenging to perform MRI based studies in many biomedical applications. In this talk I will discuss a series of improved MRI acquisition and reconstruction strategies, effectively addressing image distortions and signal loss artifacts resulting from phase inconsistencies in k-space data. Our improved p...