Biodegradable materials are developed for designing temporary medical implants, like fixation devices for fractured bones or stents. At present, polymeric biomaterials such as poly-lactic acid (PLA) are currently used in these applications. The disadvantage of polymers is a low mechanical strength, hardness and wear resistance that is the main limitation for the use in load-bearing implants. Fo...

Implant materials need to be highly biocompatible to avoid inflammation in clinical practice. Although biodegradable polymeric implants can eliminate the need for a second surgical intervention to remove the implant materials, they may produce acidic degradation products in vivo and cause non-bacterial inflammation. Here we show the strategy of "substrate-anchored and degradation-sensitive coat...

In this paper, we report the development of micromachining techniques for a biodegradable polymer for the first time. By virtue of their ability to naturally degrade in tissues, biodegradable polymers hold immense promise as new materials for implantable biomedical microdevices. This work focuses on the establishment of microfabrication processes for biodegradable microstructures and microdevic...

Biotechnology associated with medical technology has allowed biodegradable synthetic polymers to have versatile and diversified biomedical applications due interesting properties such as good cell adhesion, in vivo proliferation, degradation without harmful effects the human body. Thus, they are suitable for a variety of applications, especially those related therapeutics or pharmaceutics, exam...