نتایج جستجو برای: bioactive compound
تعداد نتایج: 156313 فیلتر نتایج به سال:
Marine sponges are an excellent source of bioactive secondary metabolites with potential therapeutic value in the treatment of diseases. One group of compounds of particular interest is the microtubule-stabilizing agents, the most well-known compound of this group being paclitaxel (Taxol), an anti-cancer compound isolated from the bark and leaves of the Pacific yew tree. This review focuses on ...
Podophyllotoxin is a bioactive aryltetraline lignan obtained from roots of Podophyllum emodi Wall. P. emodi has significance in traditional medicine which possess cytotoxic and antitumor activities. Currently column chromatography is preferred method for isolation or purification of podophyllotoxin which is laborous and time consuming activity. The present research deals with the rapid and conv...
Natural products are stored in plants, animals, and microorganisms, which referred to as "natural sources generating compounds." Strong therapeutic substances developed with the help of medicinal plants. As a source several beneficial secondary metabolites that work plant's defensive system against predators including insects, herbivores have been shown be potentially active chemicals, plant-ba...
Knowledge of the full target space of bioactive substances, approved and investigational drugs as well as chemical probes, provides important insights into therapeutic potential and possible adverse effects. The existing compound-target bioactivity data resources are often incomparable due to non-standardized and heterogeneous assay types and variability in endpoint measurements. To extract hig...
The abietane-type diterpenoid (+)-ferruginol, a bioactive compound isolated from New Zealand's Miro tree (Podocarpus ferruginea), displays relevant pharmacological properties, including antimicrobial, cardioprotective, anti-oxidative, anti-plasmodial, leishmanicidal, anti-ulcerogenic, anti-inflammatory and anticancer. Herein, we demonstrate that ferruginol (1) and some phthalimide containing an...
Background: Infectious diarrhoea is an emergent problem in both developing and developed countries for high rates of mortality in infants. In recent years, drug resistance to microbial pathogens has been commonly reported from all over the world. Medicinal plants represent a rich source of antimicrobial agents. Plants are used medicinally in different countries especially in India and are a sou...
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