In vitro expansion of mesenchymal stem cell (MSCs) into large number is necessary for their application in cell-based treatment of articular cartilage defects. On the other hand, some studies have indicated that BIO (6-Bromoindirubin-3-Oxime) possesses mitogenic effects on cell culture. The objective of the present study was to examine the effect of BIO on in vitro expansion and chondrogenic di...

In an effort to minimize the risks for scientists exposure to the infectious environment and avoiding infectious incident, high-level bio-safety laboratories are designed and constructed to improve experimental safety by preventing laboratory infectious waste causing harm to people or the environment. The possibility of high-risk pathogens spread to the public environment with flow of people an...

Safety cases offer a means for communicating information about the system safety among the system stakeholders. Recently, the requirement for a safety case has been considered by regulators for safety-critical systems. Adopting safety cases is necessarily dependent on the value added for regulatory authorities. In this work, we outline a structured approach for assessing the level of sufficienc...

Organic agricultural products are the best raw materials for food with high nutritional density (food supplements, functional foods, and nutraceuticals). The applied technologies in organic farming system use inputs free of hormones, GMOs, pesticides, antibiotics other synthetic substances - all these allow both preservation bio-availability active compounds during processing elimination toxico...

Background & Aim: Cassia angustifolia Vahl is a valuable medicinal plant that it is important for constipation treatment. According to the importance of organic agriculture in increasing the yield of medicinal plants, the effect of bio-fertilizer on quantities yields of Cassia angustifolia Vahl or Senna in Karaj region (Iran) was examined. Experimental: This research was carr...

Background & Aim: Cassia angustifolia Vahl is a valuable medicinal plant that it is important for constipation treatment. According to the importance of organic agriculture in increasing the yield of medicinal plants, the effect of bio-fertilizer on quantities yields of Cassia angustifolia Vahl or Senna in Karaj region (Iran) was examined. Experimental: This research was carr...

In many cases, crashes at intersections account for over 50% of all urban road accidents. The need to reduce these crashes has fostered considerable research on the development and evaluation of traffic safety at intersections. This paper introduces a micro-level behavioral method for estimating crash potential at signalized and unsignalized intersections for different traffic characteristics. ...