The nucleotide sequence of the nucleocapsid (N) protein gene of Berne virus (BEV; proposed family Toroviridae) was determined from two independent clones of a cDNA library. From the deduced amino acid sequence a basic protein of 18.3K was predicted. In vitro transcription and translation, followed by immunoprecipitation, were used to identify the gene. The identification was confirmed by metabo...

The implementation of parallel molecular dynamics techniques is discussed in the context of the simulation of single-site anisotropic potentials. We describe the use of both replicated data and domain decomposition approaches to molecular dynamics and present results for systems of upto 65536 Gay-Berne molecules on a range of parallel computers (Transtech i860/XP Paramid, Intel iPSC/860 Hypercu...

We present a molecular dynamics study of reentrant nematic phases using the Gay-Berne-Kihara model of a liquid crystal in nanoconfinement. At densities above those characteristic of smectic A phases, reentrant nematic phases form that are characterized by a large value of the nematic order parameter S≃1. Along the nematic director these "supernematic" phases exhibit a remarkably high self-diffu...

1. Introduction 2. Natural Law, the Human Right of Non-Discrimination and Intellectual Property Law (i) Natural Law and Intellectual Property Rights (ii) Human Rights and Intellectual Property Rights (a) International Law (aa) Non-discrimination (bb) Property rights (cc) Authors' moral and material interests (dd) Minimum standard of human rights under customary international law (b) Supranation...

INTRODUCTION ................................................................................ 431 I. THE MORAL RIGHTS DEBATE .................................................... 432 A. The Origins of Moral Rights .................................................. 432 B. The Berne Convention ........................................................... 434 C. The Limited Scope of Moral Rights in t...

We present computer simulations of the Gay-Berne model with a strong terminal dipole. We report the existence of different stable antiferroelectric interdigitated bilayered phases in this model with diverse in-plane organization. The occurrence of these phases depends crucially on the value of the molecular elongation kappa. For kappa=3 we find an interdigitated bilayered smectic-A phase (absen...

This work aims to assess the value of a generalized molecular RHD screening strategy which could replace routine serological screening of weak D by indirect antiglobulin test. Three independent studies were performed at the two Blood Transfusion Services Berne and Zurich. Donors investigated were 652 RhD negative, but RhC and/or RhE positive, 17,391 mainly Rhccee, and 8200 with normal RhCcEe ph...

We explore with Monte Carlo simulations the NMR ®nding that solutes in special nematic liquid crystal mixtures `feel' zero average electric ®eld gradient FZZ : The simulations involve solute±solvent mixtures of 1000 identical Gay± Berne ellipsoidal particles with added electric quadrupoles of varying strengths placed at particle centres. As long as all quadrupoles are suciently small, FZZ calc...

The authors present a computer simulation study of amphiphilic self-assembly performed using a computationally efficient single-site model based on Gay-Berne [J. Chem. Phys. 74, 3316 (1981)] and Lennard-Jones particles. Molecular dynamics simulations of these systems show that free self-assembly of micellar, bilayer, and inverse micelle arrangements can be readily achieved for a single model pa...

En la atención de las enfermedades pancreatobiliares, colangiopancreatografía retrógrada endoscópica (CPRE) es reconocida como el proceso estándar para su exploración y tratamiento. Como cualquier otro procedimiento, tiene potenciales complicaciones. Las más comunes son pancreatitis, hemorragia, colangitis perforación duodenal. Se presenta caso un paciente con signos choque hipovolémico grado I...