The effects of chronic administration of chloroquine commonly used for prophylaxis or treatment of malaria, rheumatoid arthritis and lupus erythematosis on the inferior colliculus (IC) of adult male and female wistar rats was studied. Seventeen rats of average weight 184g were randomly assigned into treatment (n = 10) and control (n = 7) groups. Rats in the treatment group received 2mg/kg body ...

Purpose: To assess the long-term effect of highly active antiretroviral therapy (HAART) on biochemical parameters of HIV-infected patients in University of Benin Teaching Hospital (UBTH), Benin City, Nigeria. Methods: HIV/AIDS patients on HAART for 2 8 years (297), those who were not on HAART (112, positive control), and healthy subjects (103, negative control) were recruited in the Infectious ...

Introduction: Sickle cell nephropathy is a cause of significant morbidity and mortality in patients with sickle cell disease. Traditional creatinine based assay for evaluating renal function has several limitations. Hence, the need for more sensitive markers such as β2 microglobulin (β2M). This study seeks to compare β2M with creatinine as a marker of renal damage in patients with sickle cell d...

Department of Animal Science, Faculty of Agriculture, University of Benin, Benin City, Edo State, Nigeria. E-mail: [email protected] Twenty strains of local laying birds of the Dominant Black (DBK), Frizzle Birds (FB), Naked-Neck (NK) and Normal feathers Birds (NB) each were used to access the breed influence of local chicken on plasma lipid and egg lipid profiles in layers. The experimen...

BACKGROUND There has been a dearth of comprehensive data on the profile of adverse reactions to antihypertensive medicines in the Nigerian setting despite increased use. OBJECTIVE This study was aimed to characterize the adverse reactions experienced in the homogenously black African population. METHODS The study was carried out at the University of Benin Teaching Hospital, Benin City, Nige...

OBJECTIVES To report on the changes in fibrinolytic activity in human immunodeficiency virus (HIV) infected pregnant women who are undergoing highly active antiretroviral therapy (HAART). METHODS Blood was collected from 50 HIV positive women on HAART (test subjects), and 50 HIV positive women not on HAART (controls). These women were attending the prevention of mother to child clinic (PMTCT)...

OBJECTIVE To review the pathology of lymph node disorders in adults with primary peripheral lymphadenopathy. METHODS A 20-year (1985-2004) retrospective study of lymph node biopsies at the University of Benin Teaching Hospital, Benin City, Nigeria. RESULTS Of the 427 lymph node biopsy specimens received, 238 (55.7%) were from males and 189 (44.3%) from females. Localized lymphadenopathy was...

OBJECTIVE To document the umbilical cord separation time and factors which may influence this among a cohort of infants. DESIGN Descriptive cross sectional study. SETTING Well Baby/Immunisation clinic in University of Benin teaching hospital, Benin city, Edo state, Nigeria. SUBJECTS Four hundread and ninety seven consecutive mothers with their healthy infants were documented for age, pari...

PURPOSE To analyze the cost of glaucoma medical therapy and compare it with that of surgical management in Nigeria. METHODS The cost of glaucoma drugs and that of surgical therapy in patients who attended the eye clinic of the University of Benin Teaching Hospital, Benin City, Nigeria, between December 2002 and November 2008 were calculated over a 3 year period of follow-up. Costs of medical ...

BACKGROUND The roles of physicians in oral healthcare delivery are very important due to the unequal distribution of the low oral health manpower as well as the lack of awareness of patients concerning the treatment of oral health problems by dentists in Nigeria. AIM To assess the Nigerian clinical level medical students' knowledge of dental problems and conditions in relation to the dental s...