OBJECTIVES To compare the effects and histopathological changes of botulinum neurotoxin type A and lysozyme gene injections into prostate tissue within a testosterone induced benign prostate hyperplasia rat model. MATERIALS AND METHODS 40 male Wistar rats were randomized into four Groups. Group-1: Control, Group-2: Testosterone replacement, Group-3: Testosterone+botulinum neurotoxin type A, G...

CASE REPORT A 57-year-old man presented with obstructive urinary symptoms for 6 months. Physical examination did not reveal any abnormality except for the slightly enlarged prostate. Prostate volume was estimated to be 55 mL, and serum level of prostate-specific antigen (PSA) was 5.4 ng/mL. Eight-quadrant transrectal biopsy revealed no malignancy. Transurethral prostate resection was done and p...

Aim: to improve the outcomes of surgical treatment benign prostatic hyperplasia by bipolar transurethral resection based on personalized approach. Materials and methods. Surgical prostate was carried out in 50 patients: approach, that is extensive preoperative preparation, adopted 25 cases, standard procedure implemented rest cases. Functional were assessed 1, 3 6 months aft er surgery, taking ...

The development of human benign or malignant prostatic diseases is closely associated with androgens, primarily testosterone (T) and dihydrotestosterone (DHT). T is converted to DHT by 5-alpha reductase (5-AR) isozymes. Differential expression of 5-AR isozymes is observed in both human benign and malignant prostatic tissues. 5-AR inhibitors (5-ARI) are commonly used for the treatment of benign ...

Finasteride is the 5alpha-reductase inhibitor that received clinical approval for the treatment of human benign prostate hyperplasia and androgenetic alopecia. The 5alpha-reductase is enzyme responsible for the reduction of testosterone to dihydrostestosterone, progesterone to dihydroprogesterone and deoxycorticosterone to dihydrodeoxycorticosterone, steroids modulating the action of gamma-amin...

Background: Estimating prostate volume using less invasive transabdominal ultrasonography (TAUS) instead of transrectal ultrasonography (TRUS) is of interest in terms of identifying their agreement level. Previous reports on this subject, applied general correlation coefficient as the level of agreement. This study uses Bland-Altman method to quantify TAUS and TRUS agreement on estimating prost...

This study discussed the effect of whole course comprehensive nursing after operation for benign prostatic hyperplasia (BPH). Eighty-six patients with BPH who were to undergo surgery divided into a control group and based on therapeutic method. 43 in each postoperatively given usual care group. The mental status, prostate symptoms, quality life, complications degree satisfaction compared before...

BACKGROUND Prostate gland of male reproductive system is about the size of walnut and surrounds the urethra. Most frequently encountered diseases affecting prostate are Prostatitis, Benign prostatic hyperplasia and Prostatic cancer .Our objective of study was to evaluate the spectrum and correlation of prostatic lesions with presenting complaints of patient. METHODS It was a cross-sectional s...

Giant multilocular prostatic cystadenoma (GMPC) is a rare benign tumor involving the prostate gland. Microscopically, it masquerades phyllodes tumor or transitional zone hyperplasia. We report one case of GMPC arising from the prostate central zone (CZ), presenting with long-standing aspermia associated with seminal vesicle fibrous obliteration.