the distinction between malignant and benign pheochromocytoma has always been a diagnostic challenge over the last decades. to date, the only reliable criterion is metastasis. the aim of the present study was to investigate the possible expression of pituitary-tumor transforming gene (pttg1) and retinoblastoma (rb) in benign and malignant pheochromocytoma. paraffin blocks of 44 and 11 patients ...

objectives: it is important to recognize any risk factors for the development of injuries in the athletic population. the aim of this study was to investigate the association between joint hyper mobility and low back pain in iranian hyper mobile and non-hyper mobile athletes. methods: 50 athletic patients with low back pain (age=23.20±12.79 years) and 51 healthy athletes (age=24.28±13.70) from ...

Background & Aims: Early detection and reliable differentiation of benign and malignant liver tumors could lead to improved cure rate and costs. Ultrasound image (US) is a convenient medical imaging method for interpreting liver tumors. Visual inspection of ultrasound images sometimes is combined with error and needs biopsy to confirm whether a tumor would be benign or malignant. The aim of thi...

Background: The present investigation compared the decrease in the volume of benign tumor before and after High Intensity Focused Ultrasound (HIFU) treatment to evaluate the therapeutic effects of HIFU. in terms of Lifestyle and obstetric characteristics of in patients with Benign Uterine Tumors. Materials and Methods: To collect the data on each patients’ lifestyle and obstetric characteristic...

Background: Malignant melanoma is the most aggressive form of skin cancer. In contrast to other tumors, the role of estrogen in the initiation and progression of melanoma remains unclear. The aim of this study was to evaluate estrogen receptor beta protein expression in human melanoma tissues and in the benign melanocytic lesions. Method: Twenty-one patients, 11 with cutaneous melanoma and 10 w...

background: serum lactate dehydrogenase (ldh) concentration is an indicator for tissue injury. it may be secreted locally in many conditions. for the first time, this study was performed to investigate the value of ldh level in bronchoalveolar lavage fluid (balf) in differentiation of benign from malignant single pulmonary nodules (spns) and to assess its relationship with serum ldh levels.   m...

this study aimed to investigate the frequency of varicella zoster virus (vzv) in benign and malignant breast tumors. a total of 24 carcinomas and 24 fibroadenomas paraffin embedded tumoral tissue samples were obtained from the pathology sections of toos and firoozgar hospitals in tehran, iran. all samples were collected from patients from june 2011 to february 2012. dna was extracted from all s...

background : this study evaluates estrogen and progesterone expressions in patients with ovarian tumors (both benign and malignant) and their correlation with various clinicopathological prognostic parameters. receptors for estrogen and progesterone are predictive and prognostic markers of endometrial and breast cancers. however, their clinical significance in epithelial ovarian cancer is not c...