This study aimed to investigate optimal fermentation conditions of biological acetic acid for vinegar production. Optimization was performed on 3 bacteria strains namely VMA1, VMA7 and VMAO using Response Surface Methodology (RSM). A Box-Behnken-Design (BBD) achieved with three different independent process parameters involving: temperature, original alcohol concentration one dependent variable...

A fast optimal algorithm based on the branch and bound (BBD) method is proposed for the joint detection of binary symbols of K users in a synchronous Code-Division Multiple Access (CDMA) channel with Gaussian noise. Relationships between the proposed algorithms (depth-first BBD and fast BBD) and both the decorrelating decision feedback (DF) detector and sphere decoding (SD) algorithm are clearl...

Benign breast disease (BBD) is a risk factor for breast cancer and may have a heritable component. Deficient DNA repair has been implicated in breast cancer etiology and may exert its effect before BBD, a known precursor. The association between allelic variants in DNA repair genes and BBD was examined in a cohort of women in Washington County, Maryland. BBD was defined by two criteria: (a) a p...

BACKGROUND Little generalizable information is available on the outcomes of children diagnosed with bladder and bowel dysfunction (BBD) after a urinary tract infection (UTI). Our objectives were to describe the clinical characteristics of children with BBD and to examine the effects of BBD on patient outcomes in children with and without vesicoureteral reflux (VUR). METHODS We combined data f...

Objective: To develop a Verapamil hydrochloride controlled release gastro-retentive (CRGR) tablet for once-daily dosing using the response surface Box-Behnken Design (BBD) approach improvement of bioavailability and reduction in frequency to overcome issues related conventional formulation. Methods: For optimization, 33Box-Behnken design was used. The independent variables were selected, amount...

Response surface methodology was engaged for the optimization of diverse nutritional and physical parameters for laccase production by Streptomyces chartreusis strain NBRC 12753 in the submerged fermentation process. Screening of production parameters was executed using Plackett–Burman design and the variables with statistically momentous effects on laccase production were recognized. Variables...

In this study, Seed pods of B. ceiba were used as a novel, cheap, and sustainable feedstock for second-generation bioethanol production. waste was pretreated with NaOH under different conditions using Box–Behnken design (BBD) three factors levels. Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM) to inve...

In a batch reactor, the EF advanced oxidation decolorization of aqueous solutions methyl orange MO, commercial azo reactive textile dye, was investigated in presence two different electrodes. The evaluation included various operational variables such as IC current intensity (60 mA, 80 and 100 mA), initial concentration pollutant MO (20 mg/L, 40 60 mg/L), pH solution (3, 5, 7), temperature °C, 3...

Black band disease (BBD) is a migrating, cyanobacterial dominated, sulfide-rich microbial mat that moves across coral colonies lysing coral tissue. While it is known that BBD sulfate-reducing bacteria contribute to BBD pathogenicity by production of sulfide, additional mechanisms of toxicity may be involved. Using HPLC/MS, the cyanotoxin microcystin was detected in 22 field samples of BBD colle...

The present study aimed to optimize the production of L-asparaginase from Aspergillus arenarioides EAN603 in submerged fermentation using a radial basis function neural network with specific genetic algorithm (RBFNN-GA) and response surface methodology (RSM). Independent factors used included temperature (x1), pH (x2), incubation time (x3), soybean concentration (x4). coefficient predicted mode...