The Plackett-Burman design and the Box-Behnken design, statistical methodologies, were employed for the optimization lipase and biosurfactant production by Ochrobactrum intermedium strain MZV101 in an identical broth medium for detergent applications. Environmental factor pH determined to be most mutual significant variables on production. A high concentration of molasses at high temperature an...

background nowadays, adsorption techniques are widely used to remove certain classes of pollutants from water. objectives the aim of this study was to remove ametryn from water solutions by natural zeolite nanoparticles from the semnan region of iran. materials and methods for this purpose zeolite nanoparticles were synthesized from natural zeolite using planetary ball-mill. the zeolite nanopar...

n-methylol dimethyl phosphonopropionamide (mdpa) is one of the most utilized fire resistant (fr) finishes for cotton fabrics, utilized as part of a formulation with trimethylol melamine (tmm) to acquire better crosslinking and enhanced fr properties. the system parameters of the finishing treatment were upgraded for better fr properties and low mechanical loss to the fabric by the response surf...

BACKGROUND Pichia guilliermondii was found capable of expressing the recombinant thermostable lipase without methanol under the control of methanol dependent alcohol oxidase 1 promoter (AOXp 1). In this study, statistical approaches were employed for the screening and optimisation of physical conditions for T1 lipase production in P. guilliermondii. RESULT The screening of six physical condit...

This study was undertaken to isolate ligninase-producing white-rot fungi for use in the extraction of fibre from pineapple leaf agriwaste. Fifteen fungal strains were isolated from dead tree trunks and leaf litter. Ligninolytic enzymes (lignin peroxidase (LiP), manganese peroxidase (MnP), and laccase (Lac)), were produced by solid-state fermentation (SSF) using pineapple leaves as the substrate...

Restricting the randomization of hard-to-change factors in industrial experiments is often performed by employing a split-plot design structure. From an economic perspective, these designs minimize the experimental cost by reducing the number of resets of the hard-tochange factors. In this paper, unbalanced designs are considered for cases where the subplots are relatively expensive and the exp...

Abstract Background The overall objective was to prepare a highly accurate nanocarrier system of mesalamine for the treatment ulcerative colitis with increased therapeutic efficacy and targeting. In formulation systems, optimization is critical process understanding nanoformulation variables quality aspects. goal present work determine effect independent variables, i.e., concentrations chitosan...

The aim of this study was to prepare orally disintegrating tablets (ODTs) containingdexamethasone (DEX) by direct compression method with sufficient hardness and rapiddisintegration time. In order to save time, money, and human resources in designing andimprovement of formulation, the statistical software Design Expert is used. Box–Behnkenresponse surface methodology was applied to evaluate and...

Fagus orientalis Lipsky tree leaves, which are abundant in Iran, were evaluated for removal of lead from aqueous solutions. The optimization strategy is carried out by using two level full factorial designs. Results of the two levels full factorial design (2) based on an analysis of variance demonstrated that the initial pH, contact time and concentration of biomass are statistically significan...

Fermentative biohydrogen production has been flagged as a future alternative energy source due to its various socio-economical benefits. Currently, its production is hindered by the low yield. In this work, modelling and optimization of fermentative biohydrogen producing operational setpoint conditions was carried out. A box-behnken design was used to generate twenty-nine batch experiments. The...