the pathergy phenomenon (pp) is one of the hallmarks of behcet's disease (bd). it has been reported to be positive from 17.5% to 83% of cases in different studies. pp is used as a diagnosis criterion in the dilsen criteria, the japan criteria, the international criteria, and the iran criteria. it is therefore important to know wether pp is a fix manifestation of the disease or a cyclic manifest...

Case Report We confirmed the Muckle-Wells syndrome phenotype of CAPS by NLRP3 genetic testing in a three generation family of Turkish Jewish origin, previously diagnosed with familial Behcet disease due to the presence of mucosal ulcers in several family members with the finding of the HLA-B51 antigen in at least one family member. Eight family members including a deceased grandfather, 4 of his...

OBJECTIVE Behçet disease (BD) is a vasculitis of unknown etiology, characterized by oral or genital aphtosis and uveitis. Homocysteine (hcy) is an independent risk factor for venous and arterial thrombosis. The association between hyperhomocysteinemia and thrombosis has been investigated in some studies in BD patients. However, information on this association is based only on the results of sma...

STUDY OBJECTIVES The aims of this study were to investigate the frequency of pulmonary problems in Behçet disease (BD), and to discuss lesser-known features of pulmonary BD such as clinical characteristics, analysis of prognosis, and evaluation of treatment options with respect to the previously published cases. DESIGN We conducted a comprehensive review of the literature to analyze cumulated...

Behçet's disease is a vasculitic disorder in which the aetiopathogenetic pathway has not yet been clarified. Many organs and systems may be affected in BD. The causes of the wide-ranged clinical spectrum and the variable severity of involvement, including the kidneys remain to be defined. Behçet's disease should also be considered in the differential diagnosis of AA amyloidosis as well as vascu...

A patient with Behcet's syndrome in whom multiple pulmonary artery aneurysms were completely resolved after a combined treatment with corticosteroid and chlorambucil is reported.