The recalcitrant oral ulceration (OU) and genital ulceration (GU) of Behçet disease (BD) can be very distressing and no standard therapy has been established yet. To determine the efficacy of Wet-cupping (W-C) as adjuvant treatment of oral and genital ulceration of BD, 24 patients were included in this prospective and comparative study. All patients included in the study had a recalcitrant oral...

PURPOSE Soluble antigen (S-Ag) is a member of the arrestin family of protein with which it shares a high level of homology. It is an immunologically privileged retinal antigen that can elicit experimental autoimmune uveitis (EAU) and is thought to be a target for ocular inflammatory diseases. This study was conducted to identify in humans, the immunogenic determinants of human S-Ag and to estab...

La maladie de Behçet est une vascularite inflammatoire associant plusieurs manifestations cliniques dont la pathogénie reste encore mal élucidée. L'association à une endocardite infectieuse tricuspidienne est rarement rapportée dans la littérature. Patient âgé de 39 ans, était suivi pour une maladie de Behçet depuis 7 ans ; ce diagnostic a été posé devant l'association d'une aphtose bipolaire, ...

Herpes simplex virus infection and syphilis are the most common causes of genital ulcers in the United States. Other infectious causes include chancroid, lymphogranuloma venereum, granuloma inguinale (donovanosis), secondary bacterial infections, and fungi. Noninfectious etiologies, including sexual trauma, psoriasis, Behçet syndrome, and fixed drug eruptions, can also lead to genital ulcers. A...

INTRODUCTION Parenchymal neuro-Behçet disease (NBD) is encountered in 5%-15% of Behçet disease (BD) patients and is characterized by inflammation of the brainstem and diencephalon structures. Neuronal apoptosis has been shown to participate in neuronal cell loss. Anti-neuronal antibodies have been identified in NBD patients. However, the pathogenic properties of these antibodies have not been s...

Parmi les manifestations cutanées de la maladie de Behçet, les ulcères de jambes sont exceptionnels mais gardent une implication pronostique fonctionnelle importante surtout dans les formes récidivantes et surinfectées. Nous rapportons l'observation d'un patient âgé de 42 ans porteur de maladie de Behçet depuis l'âge de 27 ans qui fût exploré pour ulcères de jambes bilatéraux, récidivants et in...

INTRODUCTION AND OBJECTIVES Behçet disease (BD) is a systemic immune-mediated vasculitis of unknown origin characterised by recurrent orogenital ulceration, ocular inflammation and skin lesions. The aim of our study was to identify ear, nose and throat (ENT) manifestations associated with BD. PATIENTS AND METHODS Retrospective review of the medical records of all patients diagnosed with BD wh...