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Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereal-based foods worldwide. At the molecular level, DON disrupts normal cell function by inhibiting protein synthesis via binding to the ribosome and by activating critical cellular kinases involved in signal transduction related to proliferation, differentiation, and apoptosis. Relative to toxicity, there are marked species diffe...
Deoxynivalenol (DON), produced by the plant pathogens Fusarium graminearum and Fusarium culmorum, is one of the most common mycotoxins, contaminating cereal and cereal-derived products. Although worldwide contamination of food and feed poses health threats to humans and animals, pigs are particularly susceptible to this mycotoxin. DON derivatives, such as deepoxy-deoxynivalenol (DOM-1), are pro...
Fusarium species produce important mycotoxins, such as deoxynivalenol (DON), nivalenol (NIV) and T-2/HT-2-toxins in cereals. The highest DON and T-2/HT-2 toxin levels in northern Europe have been found in oats. About 12%-24% of Finnish oat samples in 2012 contained >1.75 mg·kg-1 of DON, which belongs to type B trichothecenes. Fusarium graminearum is the most important DON producer in northern E...
Excretion rates of ammonia-N, nitrite-N, nitrate-N, and dissolved organic nitrogen (DON) for juvenile Litopenaeus vannamei (3.85+/-0.83 g) were quantified in response to nine different combinations of temperature (24, 28, and 32 degrees C) and salinity (10, 25, and 40 ppt) under laboratory conditions. Results indicated that L. vannamei is ammonotelic, with ammonia-N accounting for 61.9-84.3% of...
Article history: Received 8 October 2012 Received in revised form 15 October 2014 Accepted 7 November 2014 Available online xxxx Communicated by D. Sannella
Trichothecene mycotoxins such as deoxynivalenol (DON) are known to modulate the immune function, but to this date only few studies have been conducted with farm animals, especially pigs, which are regarded as most susceptible to this mycotoxin. Mitogen-stimulated proliferation of porcine blood lympho cytes was measured using two different assays, the MTT cleav age (metabolic activity) and the...
Deoxynivalenol (DON) is one of several mycotoxins produced by certain Fusarium species that frequently infect corn, wheat, oats, barley, rice, and other grains in the field or during storage. It is a toxic byproduct of Fusarium head blight in grains and feeds. Potential human exposure to DON may occur from ingestion of products made from contaminated grains. It has been detected in buckwheat, p...
The trichothecene mycotoxin deoxynivalenol (DON) is a contaminant of crops worldwide and known to cause adverse health effects in exposed animals and humans. A small survey reported the presence of DON in maize samples in Bangladesh, but these data are insufficient to assess human exposure, and also, biomonitoring data are still scarce. The present study applied biomarker analysis to investigat...
Introduction: Plusieurs facteurs font obstacles au don de sang dans les pays en développement. La présente étude avait pour objectifs d'analyser les connaissances, attitudes et pratiques de la population de Kisangani relatives au don de sang et d'identifier les obstacles au don de sang afin de guider la planification des activités de promotion du don de sang. Méthodes: L' enquête a été réalisée...
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