This study used particle swarm optimization (PSO) to determine the optimal values of effective design variables acting on the stress distribution around a quasi-triangular hole in an infinite orthotropic plate. These parameters were load angle, hole orientation, bluntness, fiber angle, and material properties, which were ascertained on the basis of an analytical method used by Lekhnitskii [3]. ...

in many structures, the applied lateral loads are comparable with gravity loads. these types of piles which are subject to high lateral load are usually divided into two categories including long and short piles. the general methods to estimate lateral bearing capacity of short and long piles are based on ultimate bearing capacity and allowable horizontal displacement respectively. in the prese...

Seismic base isolation are devices that used to limit the human and material damage caused by an earthquake. This devices diffuse the energy induced at the time of the earthquake before being transferred to the structure.The base isolated structures when subjected to the near-fault eathquakes which contain long-period velocity pulses that may coincide with the period of base isolated structures...

Cancer-induced cachexia affects most advanced cancer patients. It is characterized by anorexia, profound metabolic dysfunctions, and severe neurological disorders. Here we show that voltage-gated potassium channel (Kv) expression is impaired in the brain of tumor-bearing animals. Expression of both delayed rectifier (Kv1.1, Kv1.2, Kv1.3, Kv1.5, Kv1.6, Kv2.1, Kv3.1, Kv4.2) and A-type potassium c...

Based on the combination of improved Local Mean Decomposition (LMD), Multi-scale Permutation Entropy (MPE) and Hidden Markov Model (HMM), the fault types of bearings are diagnosed. Improved LMD is proposed based on the self-similarity of roller bearing vibration signal by extending the right and left side of the original signal to suppress its edge effect. First, the vibration signals of the ro...

When tumor-bearing mice were given diet containing fruit bodies of shiitake (L-feed), the tumor growth was apparently inhibited. To elucidate the mechanisms of this action, the effects of the L-feed on the production superoxide anion (SOA) by macrophages and the cytotoxicity of natural killer T cells were studied. When MM-46 carcinoma-bearing C3H mice were maintained on L-feed (containing 20% s...