Compounds a containing bicyclo[1.1.1]pentane (BCP) adjacent to chiral center can be prepared with high enantiomeric excess through asymmetric transfer hydrogenation (ATH) of ketones. In the reduction step, BCP occupies position distant from η6-arene catalyst. The was applied synthesis analogue antihistamine drug neobenodine.

B cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most frequent type of cancer in children. Despite progresses in curative treatment, intensive chemotherapy regimens still cause life threatening complications. A better understanding of the molecular mechanisms underlying the emergence and maintenance of BCP-ALL is fundamental for the development of novel therapies. Here, we establi...

We prove that the Besicovitch Covering Property (BCP) holds for homogeneous distances on the Heisenberg groups whose unit ball centered at the origin coincides with an Euclidean ball. We provide therefore the first examples of homogeneous distances that satisfy BCP in these groups. Indeed, commonly used homogeneous distances, such as (Cygan-)Korányi and Carnot-Carathéodory distances, are known ...

Arthroscopic shoulder surgery is a common procedure and can be performed with the patient in the lateral decubitus position (LDP) or beach chair position (BCP). Although the BCP is associated with better visualization and less bleeding, it has also been associated with hemodynamic changes and consequently cerebral hypoperfusion. Devastating events reported after surgery in the BCP were attribut...

This paper proposes new algorithms for the Binate Covering Problem (BCP), a well-known restriction of Boolean Optimization. Binate Covering finds application in many areas of Computer Science and Engineering. In Artificial Intelligence, BCP can be used for computing minimum-size prime implicants of Boolean functions, of interest in Automated Reasoning and Non-Monotonic Reasoning. Moreover, Bina...

There is a need to improve the nutritional and functional characteristics of breakfast cereal products (BCP) consumed worldwide, namely by increasing content diversity dietary fibre enrichment in micronutrients bioactive compounds. Considering high amounts fruit vegetable by-products (FVB) generated industrial processing, associated environmental issues but also their richness nutrients phytoch...

Calcium deposition diseases caused by calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals are a significant source of morbidity in the elderly. We have shown previously that both types of crystals can induce mitogenesis, as well as metalloproteinase synthesis and secretion by fibroblasts and chondrocytes. These responses may promote degradation of articular tissues...

Recent experiments show that external inplanar electric field can be employed to guide the molecular self-assembly in diblock copolymer (BCP) thin films to form lamellar nanostructures with potential applications in nanotechnology. We study this self-assembly process through a detailed coarse-grained phase-separation modeling. During the process, the free energy of the BCP films is modeled as t...

Abstract The limited options for bone repair have led to an extensive research of the field and development alloplastic xenogeneic grafts. purpose this study was evaluate with two substitutes: deproteinized bovine (DBB) biphasic calcium phosphate ceramic (BCP) in critical-size defect. A total 8-mm defects were made parietal bones rabbits (n=12). animals divided into three experimental groups: s...

COmputational INfrastructure for Operations Research Lehigh University This document will serve as a simple example for using COIN/BCP to solve an integer linear program (ILP) using branch and price (BP). Topic: Integer Linear Program, Column Generation Modules: BCP, OSI, Coin, CLP Source: AAP BP.tar.gz Data: AAP Data included in AAP BP.tar.gz Author: Matthew Galati Document: AAP BP: A COIN/BCP...