Empirical experience with genomic selection in dairy cattle suggests that the distribution of the effects of single nucleotide polymorphisms (SNPs) might be far from normality for some traits. An alternative, avoiding the use of arbitrary prior information, is the Bayesian Lasso (BL). Regular BL uses a common variance parameter for residual and SNP effects (BL1Var). We propose here a BL with di...

Bacterial cold water disease (BCWD) causes significant mortality and economic losses in salmonid aquaculture. Previously, we reported high genomic prediction accuracy of 0.72 for BCWD resistance rainbow trout using the 57 K Axiom SNP array. Due to cost phenotyping genotyping breeding programs, it is paramount know if acceptable can be obtained subsequent generation without retraining model. In ...

background: chronic obstructive pulmonary disease (copd) is usually considered one of the leading causes of death worldwide, so finding proper therapeutic strategies for this disease is of high importance. in this meta-analysis, we reviewed the existing literature on the efficacy and safety of conventional long acting beta agonists (labas) in copd patients. methods: we searched medline and goog...

introduction: the accuracy of analyzing functional mri (fmri) data is usually decreases in the presence of noise and artifact sources. a common solution in for analyzing fmri data having high noise is to use suitable preprocessing methods with the aim of data denoising. some effects of preprocessing methods on the parametric methods such as general linear model (glm) have previously been evalua...